Dale J C, Hamrick H J
Department of Laboratory Medicine and Pathology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.
Arch Pathol Lab Med. 2000 Oct;124(10):1425-8. doi: 10.5858/2000-124-1425-NBTP.
To characterize laboratory practices for neonatal bilirubin testing and to identify opportunities for improvement.
A voluntary self-assessment questionnaire was used to assess the laboratory practices of 312 laboratories subscribing to the College of American Pathologists (CAP) Excel Chemistry Proficiency Testing Program.
A range of preanalytic and analytic practices were reported. The most notable problems identified were the use of overly long capillary puncture devices (17.8%), failure to protect the specimen from light prior to analysis (3.4%), failure to use a control containing >171 micromol/L bilirubin (26.1%), use of single-level control (4.2%), and lack of established linearity limits (7.0%).
Opportunities exist to improve specimen collection, processing, and analysis for some physician-office and small-hospital laboratories.
描述新生儿胆红素检测的实验室操作特点，并确定改进机会。
采用自愿自我评估问卷对312家参加美国病理学家学会（CAP）Excel化学能力验证计划的实验室的操作进行评估。
报告了一系列分析前和分析操作。发现的最显著问题是使用过长的毛细血管穿刺装置（17.8%）、分析前未对样本进行避光保护（3.4%）、未使用胆红素含量>171微摩尔/升的对照品（26.1%）、使用单水平对照品（4.2%）以及缺乏既定的线性限度（7.0%）。
一些医师办公室和小型医院实验室在样本采集、处理和分析方面存在改进机会。
