Kietzmann M
Institut für Pharmakologie, Toxikologie und Pharmazie, Tierärztliche Hochschule Hannover.
Dtsch Tierarztl Wochenschr. 2000 Aug;107(8):337-8.
If drug treatment is necessary in large herd sizes, the administration with feed or drinking water is preferred. The use of the drinking water as a vehicle for drugs may be accompanied by several problems. An important condition for a successful medication is a good water solubility of the administered compound. The solubility is influenced by the quality of the used drinking water. The stability of the dissolved drug and incompatibilities with other water ingredients are additional limiting factors. The success of the treatment is influenced also by the taste of the medicated water which may cause a reduced water consumption. The use of tap water instead of spring water may be helpful to improve the efficacy of drug treatment via drinking water.
如果在大群体规模中需要进行药物治疗,首选通过饲料或饮用水给药。将饮用水作为药物载体可能会伴随几个问题。成功用药的一个重要条件是所给药化合物具有良好的水溶性。溶解度受所用饮用水质量的影响。溶解药物的稳定性以及与其他水成分的不相容性是另外的限制因素。治疗的成功还受加药后水的味道影响,这可能导致饮水量减少。使用自来水而非泉水可能有助于提高通过饮用水进行药物治疗的效果。