Burton A J, Backhouse O, Metcalfe T W
Leeds General Infirmary, UK.
Eye (Lond). 2000 Aug;14 ( Pt 4):594-6. doi: 10.1038/eye.2000.149.
To determine whether prilocaine is a more comfortable local infiltration anaesthetic agent than the more widely used lignocaine for minor eyelid procedures.
A prospective randomised study was undertaken to compare the discomfort between local infiltration of plain 2% prilocaine versus its equivalent, plain 2% lignocaine. One hundred and twenty-five patients were recruited. Pain was assessed subjectively using a visual analogue pain score, graded from 0 to 10.
The mean pain score for the prilocaine group was 1.82 compared with 3.19 for the lignocaine group. Using the Mann-Whitney U-test for significance, U = 1236.5; p < 0.001.
Prilocaine is a more comfortable local infiltration anaesthetic agent than lignocaine when used for minor eyelid procedures.
确定在小型眼睑手术中，丙胺卡因是否比更广泛使用的利多卡因更舒适的局部浸润麻醉剂。
进行了一项前瞻性随机研究，比较2%丙胺卡因与等量的2%利多卡因局部浸润的不适感。招募了125名患者。使用视觉模拟疼痛评分主观评估疼痛，评分范围为0至10分。
丙胺卡因组的平均疼痛评分为1.82，而利多卡因组为3.19。使用曼-惠特尼U检验进行显著性分析，U = 1236.5；p < 0.001。
在小型眼睑手术中使用时，丙胺卡因是比利多卡因更舒适的局部浸润麻醉剂。
