Chiu T F, Lee C N, Lee P I, Kao C L, Lin H C, Lu C Y, Tseng H Y, Hsu H L, Lee C Y, Huang L M
Department of Pediatrics, National Taiwan University Hospital, Taipei, ROC.
J Microbiol Immunol Infect. 2000 Sep;33(3):181-6.
Rotavirus infection is the leading cause of childhood gastroenteritis. We retrospectively reviewed cases of rotavirus gastroenteritis at National Taiwan University Hospital from January 1993 to December 1997. During the study period there were 429 patients with rotavirus infection with ages ranging from 1 day to 16 years with a median of 13 months. The male-to-female ratio was 1.2:1. Infection occurred before the age of 2 years old in 76% of patients. The seasonal peak occurred in the late winter and early spring during 1993 to 1996, but the case number increased in late spring and summer in 1997. The G serotype of the rotavirus was identified in 302 patients (70%). Vomiting and dehydration developed more frequently following infection with G1 rotaviruses, while an increased frequency of seizures was noted following G2 infection; the differences were not statistically significant. One patient had two episodes of infection; the first one was caused by G1 rotavirus, and the strain causing the second infection could not be typed. In conclusion, the results suggest that there is a strong seasonal variation in the incidence and characteristics of rotavirus infection in Taipei area. The infections caused by G1 and G2 rotaviruses were clinically indistinguishable.
轮状病毒感染是儿童肠胃炎的主要病因。我们回顾性分析了1993年1月至1997年12月期间台湾大学医院收治的轮状病毒肠胃炎病例。在研究期间，共有429例轮状病毒感染患者，年龄从1天至16岁不等，中位数为13个月。男女比例为1.2:1。76%的患者在2岁之前感染。1993年至1996年期间，季节性高峰出现在冬末和早春，但1997年春末和夏季病例数增加。302例患者（70%）的轮状病毒G血清型得以鉴定。感染G1轮状病毒后呕吐和脱水更为常见，而感染G2病毒后癫痫发作频率增加；差异无统计学意义。1例患者有两次感染发作；第一次由G1轮状病毒引起，第二次感染的毒株无法分型。总之，结果表明台北地区轮状病毒感染的发病率和特征存在强烈的季节性变化。G1和G2轮状病毒引起的感染在临床上难以区分。
