Park H C, Sohn M J, Kim E Y, Han H S, Park H S
Department of Neurosurgery, Inha University Medical Center, Choong-gu, Inchon, Korea.
Childs Nerv Syst. 2000 Sep;16(9):607-10. doi: 10.1007/PL00007302.
Clear cell meningioma, about 20 cases of which have been reported in the literature, is a morphological variant of meningioma. The authors report a case of spinal clear cell meningioma that occurred in a child. A 14-month-old girl showed gradually progressive paraparesis 1 month after she started to walk. Magnetic resonance image showed an intradural extramedullary mass compressing the conus medullaris and cauda equina. Complete excision of the tumor was done, and the patient gradually recovered from motor weakness and neurogenic bladder. Histological examinations along with immunohistochemical and ultrastructural investigations allowed a diagnosis of clear cell meningioma. During the follow-up period, a recurrent mass lesion was detected on the 8-month follow-up MR image in the same region. Because clear cell meningioma might be biologically aggressive, postoperative adjuvant therapy and close follow-up investigation should be considered.
透明细胞型脑膜瘤是脑膜瘤的一种形态学变异，文献中已报道约20例。作者报告了1例发生于儿童的脊髓透明细胞型脑膜瘤。一名14个月大的女孩在开始走路1个月后出现逐渐进展的双下肢轻瘫。磁共振成像显示硬膜内髓外肿块压迫脊髓圆锥和马尾。肿瘤被完整切除，患者的运动无力和神经源性膀胱逐渐恢复。组织学检查以及免疫组化和超微结构研究确诊为透明细胞型脑膜瘤。在随访期间，8个月的随访磁共振图像显示同一区域有复发性肿块病变。由于透明细胞型脑膜瘤可能具有生物学侵袭性，因此应考虑术后辅助治疗和密切随访。
