Ingham R J, Fox P T, Costello Ingham J, Zamarripa F
University of California, Santa Barbara 93106, USA.
Brain Lang. 2000 Nov;75(2):163-94. doi: 10.1006/brln.2000.2351.
Four adult right-handed chronic stutterers and four age-matched controls completed H(2)(15)O PET scans involving overt and imagined oral reading tasks. During overt stuttered speech prominent activations occurred in SMA (medial), BA 46 (right), anterior insula (bilateral), and cerebellum (bilateral) plus deactivations in right A2 (BA 21/22). These activations and deactivations also occurred when the same stutterers imagined they were stuttering. Some parietal regions were significantly activated during imagined stuttering, but not during overt stuttering. Most regional activations changed in the same direction when overt stuttering ceased (during chorus reading) and when subjects imagined that they were not stuttering (also during chorus reading). Controls displayed fewer similarities between regional activations and deactivations during actual and imagined oral reading. Thus overt stuttering appears not to be a prerequisite for the prominent regional activations and deactivations associated with stuttering.
四名成年右利手慢性口吃者和四名年龄匹配的对照组完成了涉及公开和想象性朗读任务的H(2)(15)O正电子发射断层扫描(PET)。在公开的口吃言语过程中，辅助运动区(内侧)、46区(右侧)、前脑岛(双侧)和小脑(双侧)出现显著激活，右侧颞上回后部(21/22区)出现失活。当同样的口吃者想象自己在口吃时，也会出现这些激活和失活。在想象口吃过程中，一些顶叶区域显著激活，但在公开口吃时没有。当公开口吃停止时(在齐声朗读期间)以及当受试者想象自己没有口吃时(同样在齐声朗读期间)，大多数区域激活朝着相同方向变化。对照组在实际和想象性朗读期间区域激活和失活之间的相似性较少。因此，公开口吃似乎不是与口吃相关的显著区域激活和失活的先决条件。
