Mason H J, Serrano-Ikkos E, Kamm M A
St. Mark's Hospital, London, England.
Am J Gastroenterol. 2000 Oct;95(10):2852-7. doi: 10.1111/j.1572-0241.2000.02313.x.
The aim of this study was to examine psychological morbidity in women with idiopathic constipation.
Three age-matched groups of 47 women with idiopathic constipation (excess straining or decreased bowel frequency), 28 healthy women, and 26 women with Crohn's disease completed a newly devised Perception of Female Self questionnaire, the Intimacy subscale of the Inventory of Interpersonal Problems, the Feminine Traits from the Bem Sex Role Inventory, and the General Health Questionnaire. Thirteen patients had a low bowel frequency (<2/wk), 30 had a normal bowel frequency, and four had increased bowel frequency (>3/day). Of 29 patients with a measured whole gut transit time, 19 had slow and 10 had normal transit.
Patients with constipation had significantly increased psychological and social morbidity (anxiety, depression, and social dysfunction) (p = 0.022), increased somatization (p = 0.019), and less satisfaction in their sexual life (p = 0.001) than healthy women. Constipated women with slow transit or decreased bowel frequency did not differ significantly from those with normal transit and bowel frequency. Women with Crohn's disease did not differ significantly on any test from healthy controls.
Women with idiopathic constipation have increased psychological morbidity, altered perception about female self, and impaired intimate relationships. These factors are not present in women with "organic" GI illness also associated with abdominal pain.
本研究旨在调查特发性便秘女性的心理疾病情况。
将47名特发性便秘女性(排便时过度用力或排便频率降低)、28名健康女性和26名克罗恩病女性分为三个年龄匹配组,她们完成了一项新设计的女性自我认知问卷、人际关系问题量表中的亲密关系分量表、贝姆性别角色量表中的女性特质量表以及一般健康问卷。13名患者排便频率低(<2次/周),30名患者排便频率正常,4名患者排便频率增加(>3次/天)。在29名测量了全肠道转运时间的患者中,19名转运缓慢,10名转运正常。
与健康女性相比,便秘患者的心理和社会疾病(焦虑、抑郁和社会功能障碍)显著增加(p = 0.022),躯体化增加(p = 0.019),性生活满意度降低(p = 0.001)。转运缓慢或排便频率降低的便秘女性与转运和排便频率正常的女性之间无显著差异。克罗恩病女性在任何测试中与健康对照均无显著差异。
特发性便秘女性的心理疾病增加,对女性自我的认知改变,亲密关系受损。这些因素在同样伴有腹痛的“器质性”胃肠道疾病女性中不存在。