Epididymitis in rams: studies on vaccine efficacy.

Simultaneous inoculation with Br. ovis bacterin plus Br. abortus strain 19 produced the greatest immunity. This procedure was not permitted, however, as widespread use of Br. abortus in sheep might pose a hazard to the brucellosis eradication program in cattle. Subsequent work demonstrated that an aluminum hydroxide adsorbed bacterin, administered as two injections spaced 3-6 weeks apart, conferred a significant and acceptable level of immunity.