Bhattacharya M, Kaur I, Kumar B
Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
J Dermatol. 2000 Sep;27(9):576-82. doi: 10.1111/j.1346-8138.2000.tb02232.x.
Clinical and epidemiological data from 232 patients with lichen planus is presented. Lichen planus constituted 0.38% of the total dermatology, outpatients diagnosed. The patient ages ranged from 8 to 76 years, most being in the age range from 20 to 49 years. Duration of disease varied from 1 month to 7 years. Both sexes were equally affected. The majority of the patients (47.4%) had classical lesions followed by hypertrophic and actinic lichen planus next in frequency. Itching was the predominant symptom in 79.3%. Limbs were the most frequent initial site of onset (55.6%). Mucosal involvement along with cutaneous lesions were observed in 16.8% and genital involvement in only 5.2%. Nail changes were observed in 15.1% of patients. A history of recurrence of the disease was obtained from 10.3% of patients. Liver disease was found to be associated in 2.2% of patients. No malignant changes were observed in any of the lesions of lichen planus.
本文呈现了232例扁平苔藓患者的临床和流行病学数据。扁平苔藓占皮肤科门诊确诊患者总数的0.38%。患者年龄从8岁至76岁不等,大多数在20至49岁年龄段。病程从1个月至7年不等。男女受累情况相同。大多数患者(47.4%)有典型皮损,其次是肥厚性和光化性扁平苔藓,发病率次之。瘙痒是79.3%患者的主要症状。四肢是最常见的初始发病部位(55.6%)。16.8%的患者观察到黏膜受累伴皮肤损害,仅5.2%的患者有生殖器受累。15.1%的患者观察到指甲改变。10.3%的患者有疾病复发史。2.2%的患者发现与肝病有关。扁平苔藓的任何皮损均未观察到恶变。