Luis-Montoya Pilar, Domínguez-Soto Luciano, Vega-Memije Elisa
Dermatology Department, General Hospital "Dr Manuel Gea González," Tlalpan, Mexico.
Pediatr Dermatol. 2005 Jul-Aug;22(4):295-8. doi: 10.1111/j.1525-1470.2005.22402.x.
Lichen planus is a disease generally considered uncommon in children. Our objective was to obtain epidemiologic data retrospectively and determine the clinical characteristics of lichen planus in Mexican children seen in our dermatology department. We found 235 patients with the clinical and histologic diagnosis of lichen planus seen over a period of 22 years and 7 months. Twenty-four (10.2%) of these patients were children (15 years of age or younger). The ratio of male to female was 1:1.2. The main clinical pattern was classic lichen planus (43.5%). Mucous membrane and nail involvement were uncommon. No family history of lichen planus or systemic disease was noted. In the international literature, the frequency of lichen planus varied from 2.1% to 11.2% of the pediatric population. In the majority of studies no significant gender predominance was identified. Most patients had the classic variety of lichen planus. Reported mucosal involvement was rare, except in India and Kuwait. Frequency of nail involvement ranged from 0% to 16.6%. Little evidence of systemic disease or family history was found.
扁平苔藓是一种普遍认为在儿童中不常见的疾病。我们的目的是回顾性地获取流行病学数据，并确定在我们皮肤科就诊的墨西哥儿童扁平苔藓的临床特征。我们发现了235例经临床和组织学诊断为扁平苔藓的患者，这些患者是在22年零7个月的时间里确诊的。其中24例（10.2%）为儿童（15岁及以下）。男女比例为1:1.2。主要临床类型为经典型扁平苔藓（43.5%）。黏膜和指甲受累情况不常见。未发现扁平苔藓家族史或系统性疾病家族史。在国际文献中，扁平苔藓在儿科人群中的发生率为2.1%至11.2%。在大多数研究中，未发现明显的性别优势。大多数患者患有经典型扁平苔藓。除了在印度和科威特，报道的黏膜受累情况很少见。指甲受累的发生率在0%至16.6%之间。几乎没有发现系统性疾病或家族史的证据。
