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羧苄青霉素-氨基糖苷类及头孢噻吩-氨基糖苷类联合用药对肠球菌的体外抗菌效果

Effectiveness of carbenicillin - aminoglycoside and of cephalothin-aminoglycoside combinations against enterococci in vitro.

作者信息

Klastersky J, Daneau D

出版信息

Pathol Biol (Paris). 1975 May;23(5):345-8.

PMID:1105331
Abstract

Combination of carbenicillin and cephalothin with various aminoglycosides (gentamicin, sisomicin, tobramycin, kanamycin and amikacin) were studied in vitro using 20 strains of enterococci isolated from clinical material. The addition of the aminoglycosides to carbenicillin increased the rate of bactericidal action of carbenicillin on most strains. Little benefit was obtained by adding the aminoglycosides to cephalothin and antagonistic action has been observed on some strains.

摘要

使用从临床材料中分离出的20株肠球菌，对羧苄青霉素、头孢噻吩与各种氨基糖苷类药物（庆大霉素、西索米星、妥布霉素、卡那霉素和阿米卡星）的组合进行了体外研究。在羧苄青霉素中添加氨基糖苷类药物可提高其对大多数菌株的杀菌作用速率。在头孢噻吩中添加氨基糖苷类药物几乎没有益处，并且在一些菌株上观察到了拮抗作用。

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Effectiveness of carbenicillin - aminoglycoside and of cephalothin-aminoglycoside combinations against enterococci in vitro.羧苄青霉素-氨基糖苷类及头孢噻吩-氨基糖苷类联合用药对肠球菌的体外抗菌效果
Pathol Biol (Paris). 1975 May;23(5):345-8.
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