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[阿尔茨海默型痴呆患者照料者的负担与生活质量]

[Burden and quality of life in carers of patients with Alzheimer type dementia].

作者信息

Garre-Olmo J, Hernández-Ferrándiz M, Lozano-Gallego M, Vilalta-Franch J, Turón-Estrada A, Cruz-Reina M M, Camps-Rovira G, López-Pousa S

机构信息

Unidad de Valoracion de la Memoria y las Demencias, Hospital Santa Caterina, Girona, Espana.

出版信息

Rev Neurol. 2000;31(6):522-7.

Abstract

OBJECTIVE

To analyze the factors which affect the burden and quality of life in carers of patients with Alzheimer's disease.

MATERIAL AND METHODS

From a sample of 234 carers of patients in the Unit for Assessment of Memory and Dementia with a diagnosis of probable Alzheimer's disease, according to the scale of National Institute of Neurological and Communicative Disorders and Stroke/Alzheimer's Disease and Related Disorders Association (NINCS-ADRDA), and of minimal or slight severity, according to the Cambridge Mental Disorders of the Elderly Examination (CAMDEX) criteria, we obtained sociodemographic variables and administered the following questionnaires: Neuropsychiatric Inventory (NPI), Rapid Disability Rating Scale (RDRS-2), Quality of Life Questionnaire (QLQ) and Burden Interview (BI).

RESULTS

The sex of the carers, the hours of attention to the basic activities of daily life (BADL) and the Cambridge Cognitive Examination (CAMCOQ), Minimental State Examination (MMSE), QLQ, NPI and RDRS-2 scores were related to the BI score. Multiple regression accepted the scoring for NPI, RDRS-2 and QLQ in the model. The QLQ score was associated with male sex of the patient, the age of the carer, employment status, whether or not he lived with the patient, with the family relationship, the hours of attention to the BADL and the scores on CAMCOG, MMSE, RDRS-2, NPI and BI. The multiple regression model included the age of the carer, the BI score and the hours of attention to the BADL.

CONCLUSION

The non-cognitive symptoms, functional disability and poor perception of quality of life are factors affecting the burden and age of the carer, the hours of attention to the BADL and the burden affecting quality of life.

摘要

目的

分析影响阿尔茨海默病患者照料者负担及生活质量的因素。

材料与方法

从记忆与痴呆评估单元的234名阿尔茨海默病患者照料者样本中选取,这些患者根据美国国立神经疾病和中风研究所/阿尔茨海默病及相关疾病协会(NINCS - ADRDA)量表被诊断为可能患有阿尔茨海默病,且根据剑桥老年精神障碍检查表(CAMDEX)标准为轻度或轻微严重程度。我们获取了社会人口统计学变量,并发放了以下问卷:神经精神科问卷(NPI)、快速残疾评定量表(RDRS - 2)、生活质量问卷(QLQ)和负担访谈(BI)。

结果

照料者的性别、对日常生活基本活动(BADL)的照料时长以及剑桥认知检查(CAMCOQ)、简易精神状态检查表(MMSE)、QLQ、NPI和RDRS - 2得分与BI得分相关。多元回归分析接受了模型中NPI、RDRS - 2和QLQ的评分。QLQ得分与患者的男性性别、照料者年龄、就业状况、是否与患者同住、家庭关系、对BADL的照料时长以及CAMCOG、MMSE、RDRS - 2、NPI和BI的得分相关。多元回归模型包括照料者年龄、BI得分和对BADL的照料时长。

结论

非认知症状、功能残疾和对生活质量的低感知是影响照料者负担、照料者年龄、对BADL的照料时长以及影响生活质量的负担的因素。

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