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意大利南部(普利亚地区)阿尔巴尼亚难民中的乙肝病毒、丙肝病毒和丁肝病毒感染情况

HBV, HCV and HDV infections in Albanian refugees in Southern Italy (Apulia region).

作者信息

Chironna M, Germinario C, Lopalco P L, Quarto M, Barbuti S

机构信息

Department of Internal Medicine and Public Health, University of Bari, Italy.

出版信息

Epidemiol Infect. 2000 Aug;125(1):163-7. doi: 10.1017/s0950268899004215.

Abstract

The seroprevalence of hepatitis B, C and D markers was assessed in a sample of 670 Albanian refugees in Southern Italy in 1997. The mean age was 25 years (S.D. = 12.3). Of study subjects 62.1% (95% CI: 58.4-65.7) were positive for anti-HBc antibodies and 13.6% (95% CI: 10.9-16.1) for HBsAg. The prevalence of anti-HBs was 47.6% (95% CI: 43.8-51.3). Among HBsAg carriers the prevalence of HBeAg was 7.7% (95% CI: 2.2-13.1). The highest carrier rate for HBsAg (25.5%; 95% CI: 16.7-34.3) was found in the age group 21-25 years. A relevant finding was a prevalence of HBsAg of 8.1% in children 10 years and under. The prevalence of anti-HCV antibodies was 0.3% (95% CI: 0.0-0.7) while only one of the HBsAg carriers was positive for anti-HDV (1.1%, 95% CI: 0-3.2). In Albania, hepatitis B infection represents a public health priority that should be addressed by a universal vaccination campaign.

摘要

1997年,在意大利南部的670名阿尔巴尼亚难民样本中评估了乙肝、丙肝和丁肝标志物的血清流行率。平均年龄为25岁(标准差=12.3)。在研究对象中,62.1%(95%置信区间:58.4 - 65.7)的抗-HBc抗体呈阳性,13.6%(95%置信区间:10.9 - 16.1)的HBsAg呈阳性。抗-HBs的流行率为47.6%(95%置信区间:43.8 - 51.3)。在HBsAg携带者中,HBeAg的流行率为7.7%(95%置信区间:2.2 - 13.1)。21 - 25岁年龄组的HBsAg携带率最高(25.5%;95%置信区间:16.7 - 34.3)。一个相关发现是10岁及以下儿童的HBsAg流行率为8.1%。抗-HCV抗体的流行率为0.3%(95%置信区间:0.0 - 0.7),而在HBsAg携带者中只有一人抗-HDV呈阳性(1.1%,95%置信区间:0 - 3.2)。在阿尔巴尼亚,乙肝感染是一个公共卫生重点问题,应通过全民疫苗接种运动加以解决。

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