雅典难民中乙肝和丙肝标志物的流行情况。
Prevalence of hepatitis B and C markers among refugees in Athens.
作者信息
Roussos Anastasios, Goritsas Constantin, Pappas Thomas, Spanaki Maria, Papadaki Panagiota, Ferti Angeliki
机构信息
Department of Internal Medicine, General Regional Hospital Sotiria, Athens, Greece.
出版信息
World J Gastroenterol. 2003 May;9(5):993-5. doi: 10.3748/wjg.v9.i5.993.
AIM
To assess the prevalence of hepatitis B and C serological markers in a population of refugees living in Athens.
METHODS
One hundred and thirty refugees (81 males and 49 females, mean age +/-SD: 31.7+/-8 years) were included in the study. The hepatitis B virus surface antigen (HBsAg), the hepatitis B virus core antibody (anti-HBc) and the hepatitis C virus antibody (anti-HCV) were detected using a third-generation immunoassay.
RESULTS
Twenty individuals (15.4 %) were HBsAg positive and 69 (53.1 %) were anti-HBc positive. The prevalence of HBsAg and anti-HBc was higher among refugees from Albania and Asia (statistical significant difference, P<0.008 and P<0.001 respectively). The prevalence of these markers was found irrelevant to age or sex. Anti-HCV was detected in the serum of 3 individuals (2.3 %). No differences among age, sex or ethnicity regarding anti-HCV prevalence were found.
CONCLUSION
It can be concluded that refugees living in Athens are an immigrant population characterized by a high incidence of HBV infection. The prevalence of HBV markers is higher among refugees from Albania and Asia. It is therefore believed that the adherence to general precautions and the initiation of HBV vaccination programs will be necessary in the future, especially in these communities. Although the prevalence of HCV infection seems to be relatively low, extended epidemiological surveys are needed to provide valid results.
目的
评估居住在雅典的难民群体中乙型和丙型肝炎血清学标志物的流行情况。
方法
130名难民（81名男性和49名女性，平均年龄±标准差：31.7±8岁）纳入本研究。采用第三代免疫分析法检测乙型肝炎病毒表面抗原（HBsAg）、乙型肝炎病毒核心抗体（抗-HBc）和丙型肝炎病毒抗体（抗-HCV）。
结果
20人（15.4%）HBsAg阳性，69人（53.1%）抗-HBc阳性。来自阿尔巴尼亚和亚洲的难民中HBsAg和抗-HBc的流行率较高（差异有统计学意义，P分别<0.008和P<0.001）。发现这些标志物的流行率与年龄或性别无关。3人（2.3%）血清中检测到抗-HCV。在抗-HCV流行率方面，未发现年龄、性别或种族之间存在差异。
结论
可以得出结论，居住在雅典的难民是一个以乙肝病毒感染发生率高为特征的移民群体。来自阿尔巴尼亚和亚洲的难民中乙肝病毒标志物的流行率较高。因此，人们认为未来有必要坚持采取一般预防措施并启动乙肝疫苗接种计划，尤其是在这些社区。虽然丙肝病毒感染的流行率似乎相对较低，但需要进行广泛的流行病学调查以提供有效的结果。
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