Singh J, Balakrishnan N, Bhardwaj M, Amuthadevi P, George E G, Subramani K, Soundararajan K, Appavoo N C, Jain D C, Ichhpujani R L, Bhatia R, Sokhey J
National Institute of Communicable Diseases, Delhi, India.
Epidemiol Infect. 2000 Aug;125(1):195-200. doi: 10.1017/s0950268899003866.
Dengue fever (DF) or dengue haemorrhagic fever (DHF) has not previously been reported in Coimbatore and Erode districts in Tamil Nadu in India. In 1998, 20 hospitalized cases of fever tested positive for dengue virus IgM and/or IgG antibodies. All of them had dengue-compatible illness, and at least four had DHF. Two of them died. Sixteen cases were below 10 years of age. The cases were scattered in 15 distantly located villages and 5 urban localities that had a high Aedes aegypti population. Although the incidence of dengue-like illness has not increased recently, almost 89% (95/107) of samples from healthy persons in the community tested positive for dengue IgG antibodies. The study showed that dengue has been endemic in the area, but was not suspected earlier. A strong laboratory-based surveillance system is essential to monitor and control DF/DHF.
印度泰米尔纳德邦的哥印拜陀和埃罗德地区此前未曾报告过登革热（DF）或登革出血热（DHF）。1998年，20例住院发热病例的登革病毒IgM和/或IgG抗体检测呈阳性。他们都患有与登革热相符的疾病，至少有4例患有登革出血热。其中2例死亡。16例病例年龄在10岁以下。这些病例分布在15个位置偏远的村庄和5个人口密集的城市地区，这些地方埃及伊蚊数量众多。尽管最近类似登革热疾病的发病率没有增加，但社区中健康人的样本中几乎89%（95/107）的登革IgG抗体检测呈阳性。该研究表明，登革热在该地区一直是地方病，但此前未被怀疑。一个强大的基于实验室的监测系统对于监测和控制登革热/登革出血热至关重要。
