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一名额颞叶痴呆患者和一名阿尔茨海默病患者的虚构症。

Confabulation in a patient with fronto-temporal dementia and a patient with Alzheimer's disease.

作者信息

Nedjam Z, Dalla Barba G, Pillon B

机构信息

U.324 INSERM, Centre Paul Broca, Paris, France.

出版信息

Cortex. 2000 Sep;36(4):561-77. doi: 10.1016/s0010-9452(08)70538-0.

DOI:10.1016/s0010-9452(08)70538-0
PMID:11059455
Abstract

This paper describes two patients, O.I. and B.Y., with a confabulatory syndrome. O.I. was diagnosed with probable fronto-temporal dementia, whereas B.Y. met the criteria for probable Alzheimer's disease. O.I., but not B.Y., was impaired on tests of frontal/executive functions, and performed better than B.Y. on clinical tests of memory. Both patients confabulated in episodic/autobiographical memory tasks and in personal future planning tasks. B.Y. confabulated also in a semantic memory task. It is argued that the pattern of confabulation and the cognitive profile shown by the two patients is explained better by the hypothesis proposed by Dalla Barba and co-workers (Dalla Barba et al., 1997b) than by current theories of confabulation.

摘要

本文描述了两名患有虚构综合征的患者,O.I. 和B.Y.。O.I. 被诊断为可能患有额颞叶痴呆,而B.Y. 符合可能患有阿尔茨海默病的标准。O.I. 在额叶/执行功能测试中受损,但B.Y. 未受损,且O.I. 在记忆临床测试中的表现优于B.Y.。两名患者在情景/自传体记忆任务和个人未来规划任务中均出现虚构。B.Y. 在语义记忆任务中也出现虚构。有人认为,与当前的虚构理论相比,Dalla Barba及其同事提出的假设(Dalla Barba等人,1997b)能更好地解释这两名患者的虚构模式和认知概况。

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