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物质滥用与虚假记忆形成的易感性:一项系统评价与荟萃分析。

Substance abuse and susceptibility to false memory formation: a systematic review and meta-analysis.

作者信息

Caetano Tânia, Pinho Maria Salomé, Ramadas Eduardo, Lopes Jessica, Areosa Timóteo, Ferreira Daniela, Dixe Maria Dos Anjos

机构信息

Faculty of Psychology and Educational Sciences of University of Coimbra, Center for Research in Neuropsychology and Cognitive and Behavioral Intervention (CINEICC), University of Coimbra, Coimbra, Portugal.

Faculty of Psychology and Educational Sciences of University of Coimbra, Neuropsychological Assessment and Ageing Processes (NAAP), University of Coimbra, Coimbra, Portugal.

出版信息

Front Psychol. 2023 May 5;14:1176564. doi: 10.3389/fpsyg.2023.1176564. eCollection 2023.

Abstract

BACKGROUND

Substance abuse has an impact on various cognitive domains, including memory. Even though this impact has been extensively examined across different subdomains, false memory has been sparsely studied. This systematic review and meta-analysis seek to synthesize the current scientific data concerning false memory formation in individuals with a history of substance abuse.

METHODS

PubMed, Scopus, the Cochrane Library, Web of Science, and PsycINFO were searched to identify all experimental and observational studies in English, Portuguese, and Spanish. Studies were then examined by four independent reviewers and, if they met the inclusion criteria, assessed for their quality. The Cochrane Risk of Bias Tool for randomized controlled trials (RCT) and the Joanna Briggs Institute (JBI) critical appraisal checklists for quasi-experimental and analytic cross-sectional studies were used to assess the risk of bias.

RESULTS

From the 443 screened studies, 27 (and two more from other sources) were considered eligible for full-text review. A final 18 studies were included in the present review. Of these, 10 were conducted with alcoholics or heavy drinkers, four focused on ecstasy/polydrug users, three were done with cannabis users and one focused on methadone maintenance patients with current cocaine dependence. Regarding false memory type, 15 studies focused on false recognition/recall, and three on provoked confabulation.

CONCLUSIONS

None but one of the studies considering false recognition/recall of critical lures found any significant differences between individuals with a history of substance abuse and healthy controls. However, most of the studies taking into account false recognition/recall of related and unrelated events found that individuals with a history of substance abuse showed significantly higher rates of false memories than controls. Future research should continue to consider different types of false memories as well as their potential association with relevant clinical variables.

SYSTEMATIC REVIEW REGISTRATION

https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=266503, identifier: CRD42021266503.

摘要

背景

药物滥用会对包括记忆在内的各种认知领域产生影响。尽管这种影响已在不同子领域进行了广泛研究,但对错误记忆的研究却很少。本系统评价和荟萃分析旨在综合有关有药物滥用史个体错误记忆形成的当前科学数据。

方法

检索了PubMed、Scopus、Cochrane图书馆、Web of Science和PsycINFO,以识别所有英文、葡萄牙文和西班牙文的实验性和观察性研究。然后由四名独立评审员对研究进行审查,若符合纳入标准,则评估其质量。使用Cochrane随机对照试验偏倚风险工具(RCT)以及乔安娜·布里格斯研究所(JBI)针对准实验性和分析性横断面研究的批判性评价清单来评估偏倚风险。

结果

在筛选的443项研究中,27项(另有两项来自其他来源)被认为符合全文审查的条件。本综述最终纳入了18项研究。其中,10项研究针对酗酒者或重度饮酒者,4项聚焦于摇头丸/多种药物使用者,3项针对大麻使用者,1项关注目前有可卡因依赖的美沙酮维持治疗患者。关于错误记忆类型,15项研究聚焦于错误识别/回忆,3项关注诱发性虚构。

结论

在考虑关键诱饵的错误识别/回忆的研究中,只有一项发现有药物滥用史的个体与健康对照之间存在显著差异。然而,大多数考虑相关和不相关事件错误识别/回忆的研究发现,有药物滥用史的个体错误记忆发生率显著高于对照组。未来的研究应继续考虑不同类型的错误记忆及其与相关临床变量的潜在关联。

系统评价注册

https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=266503,标识符:CRD42021266503

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/712a/10196796/e7c1b01f53ca/fpsyg-14-1176564-g0001.jpg

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