Pierpaoli W, Besedovsky H O
Br J Exp Pathol. 1975 Apr;56(2):180-2.
Implantation of cell impermeable Millipore chambers containing thymuses from normal newborn donors into athymic mice does not confer on them the capability to reject allogeneic skin grafts. The same deficiency is manifested when skin grafted female nude mice are pregnant of foetuses with normal thymuses. These data are thus in sharp contrast to those previously reported for thymic factors reconstituting neonatally thymectomized mice.
将含有正常新生供体胸腺的细胞不可渗透的微孔小室植入无胸腺小鼠体内,并不能赋予它们排斥同种异体皮肤移植的能力。当移植了皮肤的雌性裸鼠怀有具有正常胸腺的胎儿时,也会出现同样的缺陷。因此,这些数据与先前报道的关于重建新生期胸腺切除小鼠的胸腺因子的数据形成了鲜明对比。