Cho K J, Khang S K, Koh J S, Chung J H, Lee S S
Department of Pathology, University of Ulsan College of Medicine, Seoul, Korea.
J Korean Med Sci. 2000 Oct;15(5):545-50. doi: 10.3346/jkms.2000.15.5.545.
Ocular sebaceous carcinoma (OSC) is an uncommon malignancy with a potential to recur and metastasize. Some characteristics of sebaceous carcinoma, such as female preponderance, shown in the present series during 11-year period at Korea Cancer Center Hospital, led us to study their hormone receptors and c-erbB-2 expression. c-erbB-2 overexpression was very common (83%) in OSC, and was not associated with pathologic findings or clinical outcome. Interestingly, estrogen and progesterone receptor was detected in 4 and 2 cases, respectively, suggesting a role of hormonal influence on this neoplasm. Immunohistochemical and clinicopathologic features of 18 cases of OSC in Korea are presented.
眼部皮脂腺癌（OSC）是一种罕见的恶性肿瘤，具有复发和转移的可能性。在韩国癌症中心医院11年期间的本系列研究中，皮脂腺癌的一些特征，如女性占优势，促使我们研究其激素受体和c-erbB-2表达。c-erbB-2过表达在OSC中非常常见（83%），且与病理结果或临床结局无关。有趣的是，分别在4例和2例中检测到雌激素和孕激素受体，提示激素对该肿瘤有影响作用。本文介绍了韩国18例OSC的免疫组织化学和临床病理特征。
