Toyota N, Asaga H, Hirokawa M, Iizuka H
Department of Dermatology, Asahikawa Medical College, Japan.
Dermatology. 1994;188(1):69-71. doi: 10.1159/000247091.
We present a case of skin metastasis from follicular thyroid carcinoma which developed on the scalp of a 72-year-old man. The lesion was noticed 1 month after a surgical excision of the primary thyroid carcinoma and gradually enlarged during the past 11 months. A biopsy from the nodule showed mostly well-differentiated thyroid follicular structures with colloid material. Tumor cells showed mild variation of nuclear size and shape in almost all areas. We performed immunohistochemistry using antithyroglobulin antibody, which established the diagnosis of a metastatic lesion from thyroid follicular carcinoma. Total thyroidectomy and 131I radiotherapy were performed. No further metastasis has been discovered during the last 18 months.
我们报告一例72岁男性头皮发生的滤泡状甲状腺癌皮肤转移病例。该病变在原发性甲状腺癌手术切除后1个月被发现,并在过去11个月中逐渐增大。结节活检显示大部分为分化良好的甲状腺滤泡结构,伴有胶质物质。肿瘤细胞在几乎所有区域均显示出核大小和形状的轻度变异。我们使用抗甲状腺球蛋白抗体进行免疫组化,确诊为甲状腺滤泡癌转移灶。患者接受了全甲状腺切除术和131I放射治疗。在过去18个月中未发现进一步转移。