Komócsi A, Tóvári E, Kovács J, Czirják L
2nd Department of Internal Medicine, University Medical School of Pécs, Hungary.
Clin Exp Rheumatol. 2000 Sep-Oct;18(5):622-4.
A 51-year-old female developed linear-like scleroderma in the left thigh following a linear wound caused by a car accident. 27 years later she also developed a typical diffuse cutaneous systemic sclerosis with extensive skin involvement and bibasilar pulmonary fibrosis. The second case is a 39-year-old female who had a history of Raynaud's phenomenon since early childhood. She developed a morphea following a burning injury of the left thigh. 17 years later she also developed a typical limited cutaneous systemic sclerosis with sclerodactyly, skin ulcers and subcutaneous calcinosis. The third case is a 43-year-old female who developed a typical morphea of the right elbow around the site of a previous local corticosteroid injection. The two remarkable points of these 3 cases are the possible role of physical injury in the provocation of localized scleroderma and in the first 2 cases the unusual later development of a systemic form of scleroderma.
一名51岁女性在遭遇车祸导致的线性伤口后，左大腿出现线状硬皮病。27年后，她又患上了典型的弥漫性皮肤系统性硬化症，皮肤广泛受累，并伴有双肺基底纤维化。第二例是一名39岁女性，自幼有雷诺现象病史。她在左大腿烧伤后出现了硬斑病。17年后，她又患上了典型的局限性皮肤系统性硬化症，伴有指硬皮病、皮肤溃疡和皮下钙质沉着。第三例是一名43岁女性，在先前局部注射皮质类固醇的部位周围出现了右肘典型的硬斑病。这3例病例的两个显著特点是身体损伤在诱发局限性硬皮病中可能起的作用，以及在前两例中系统性硬皮病的异常后期发展。
