大肠杆菌K-12链霉素抗性（strA）突变体中重复基因的丢失增加。
Increased loss of duplicated genes in streptomycin-resistant (strA) mutants of Escherichia coli k-12.
作者信息
Simonian M H, Mosteller R D
出版信息
J Bacteriol. 1976 Jan;125(1):382-4. doi: 10.1128/jb.125.1.382-384.1976.
Abstract
The recombination-dependent loss of a duplicated portion of the Escherichia coli chromosome is five- to tenfold greater in strains containing streptomycin resistance (strA) mutations than in the strA+ parental strain. Streptomycin (500 mug/ml) partially reverses the increase. These results suggest an interaction between strA mutations and recombination.
摘要
在含有链霉素抗性（strA）突变的大肠杆菌菌株中，染色体重复部分依赖重组的缺失比strA+亲本菌株高五到十倍。链霉素（500微克/毫升）可部分逆转这种增加。这些结果表明strA突变与重组之间存在相互作用。
相似文献
1
Increased loss of duplicated genes in streptomycin-resistant (strA) mutants of Escherichia coli k-12.大肠杆菌K-12链霉素抗性（strA）突变体中重复基因的丢失增加。
J Bacteriol. 1976 Jan;125(1):382-4. doi: 10.1128/jb.125.1.382-384.1976.
2
Development of auxotrophy by streptomycin-resistant mutation.通过抗链霉素突变产生营养缺陷型
J Bacteriol. 1974 Jun;118(3):1179-80. doi: 10.1128/jb.118.3.1179-1180.1974.
3
Growth of bacteriophages MS2 and T7 on streptomycin-resistant mutants of Escherichia coli.噬菌体MS2和T7在大肠杆菌链霉素抗性突变体上的生长情况。
J Bacteriol. 1975 Feb;121(2):670-4. doi: 10.1128/jb.121.2.670-674.1975.
4
The genetic background for streptomycin resistance in Escherichia coli influences the distribution of MICs.大肠杆菌中链霉素抗性的遗传背景会影响最低抑菌浓度的分布。
J Antimicrob Chemother. 2005 Jul;56(1):87-90. doi: 10.1093/jac/dki150. Epub 2005 May 16.
5
Genetic characterization of streptomycin-resistant and -dependent mutants of Escherichia coli K12.大肠杆菌K12链霉素抗性和依赖性突变体的遗传特征分析。
Mol Gen Genet. 1974 Apr 9;130(1):47-64. doi: 10.1007/BF00270518.
6
A link between streptomycin and rifampicin mutation.链霉素与利福平突变之间的联系。
Proc Natl Acad Sci U S A. 1975 Jun;72(6):2084-7. doi: 10.1073/pnas.72.6.2084.
7
The role of misrepair processes in the isolation of new types of streptomycin-resistant mutants in Escherichia coli.错修复过程在大肠杆菌新型链霉素抗性突变体分离中的作用。
Mol Gen Genet. 1977 Dec 9;157(3):313-8. doi: 10.1007/BF00268668.
8
Genetic analysis of a streptomycin-resistant Escherichia coli mutant temperature-sensitive for nonsense suppression.对链霉素抗性且对无义抑制温度敏感的大肠杆菌突变体的遗传分析。
Mol Gen Genet. 1982;188(1):149-55. doi: 10.1007/BF00333010.
9
Streptomycin resistance (rpsL) produces an absolute requirement for polyamines for growth of an Escherichia coli strain unable to synthesize putrescine and spermidine [delta(speA-speB) delta specC].链霉素抗性（rpsL）使得无法合成腐胺和亚精胺的大肠杆菌菌株[Δ（speA-speB）ΔspecC]生长绝对需要多胺。
J Bacteriol. 1981 Aug;147(2):702-4. doi: 10.1128/jb.147.2.702-704.1981.
10
The dominance of streptomycin sensitivity re-examined.链霉素敏感性的优势再探讨。
Proc Natl Acad Sci U S A. 1969 Mar;62(3):979-85. doi: 10.1073/pnas.62.3.979.
引用本文的文献
1
Genetic instability associated with the aroC321 allele in Salmonella typhimurium involves genetic duplication.鼠伤寒沙门氏菌中与aroC321等位基因相关的遗传不稳定性涉及基因重复。
Mol Gen Genet. 1983;190(2):183-8. doi: 10.1007/BF00330638.
2
Genetic and segregation analysis of Escherichia coli strains containing a tandem duplication of the trpD-purB region of the chromosome.含有染色体trpD-purB区域串联重复的大肠杆菌菌株的遗传与分离分析。
J Bacteriol. 1978 Feb;133(2):650-60. doi: 10.1128/jb.133.2.650-660.1978.
本文引用的文献
1
PHENOTYPIC REPAIR BY STREPTOMYCIN OF DEFECTIVE GENOTYPES IN E. COLI.链霉素对大肠杆菌缺陷基因型的表型修复作用
Proc Natl Acad Sci U S A. 1964 Mar;51(3):487-93. doi: 10.1073/pnas.51.3.487.
2
INTERACTION OF STREPTOMYCIN AND A SUPPRESSOR FOR GALACTOSE FERMENTATION IN E. COLI K-12.链霉素与大肠杆菌K-12中半乳糖发酵抑制因子的相互作用
Proc Natl Acad Sci U S A. 1964 Apr;51(4):678-82. doi: 10.1073/pnas.51.4.678.
3
Chromosomal alterations affecting the regulation of histidine biosynthetic enzymes in Salmonella.影响沙门氏菌中组氨酸生物合成酶调控的染色体改变。
J Mol Biol. 1963 Jul;7:23-42. doi: 10.1016/s0022-2836(63)80016-9.
4
The genetic basis of hyper-synthesis of beta-galactosidase.β-半乳糖苷酶过度合成的遗传基础。
Genetics. 1963 Feb;48(2):157-69. doi: 10.1093/genetics/48.2.157.
5
Acetylornithinase of Escherichia coli: partial purification and some properties.大肠杆菌的乙酰鸟氨酸酶：部分纯化及某些性质
J Biol Chem. 1956 Jan;218(1):97-106.
6
Role of ribosomes in streptomycin-activated suppression.核糖体在链霉素激活的抑制作用中的角色。
Proc Natl Acad Sci U S A. 1965 Oct;54(4):1076-83. doi: 10.1073/pnas.54.4.1076.
7
Polarity and enzyme functions in mutants of the first three genes of the tryptophan operon of Escherichia coli.大肠杆菌色氨酸操纵子前三个基因的突变体中的极性和酶功能。
Genetics. 1971 Dec;69(4):409-33. doi: 10.1093/genetics/69.4.409.
8
Ribosomal discrimination of tRNAs.核糖体对转运RNA的识别
Nat New Biol. 1971 Dec 29;234(52):261-4. doi: 10.1038/newbio234261a0.
9
A ribosomal ambiguity mutation.核糖体模糊突变。
J Mol Biol. 1969 Jan 14;39(1):95-112. doi: 10.1016/0022-2836(69)90336-2.
10
Duplication of the structural gene for glycyl-transfer RNA synthetase in Escherichia coli.大肠杆菌中甘氨酰 - 转移RNA合成酶结构基因的复制。
J Mol Biol. 1971 Jun 14;58(2):595-610. doi: 10.1016/0022-2836(71)90374-3.
Zotero 插件