大肠杆菌K-12链霉素抗性（strA）突变体中重复基因的丢失增加。
Increased loss of duplicated genes in streptomycin-resistant (strA) mutants of Escherichia coli k-12.
作者信息
Simonian M H, Mosteller R D
出版信息
J Bacteriol. 1976 Jan;125(1):382-4. doi: 10.1128/jb.125.1.382-384.1976.
Abstract
The recombination-dependent loss of a duplicated portion of the Escherichia coli chromosome is five- to tenfold greater in strains containing streptomycin resistance (strA) mutations than in the strA+ parental strain. Streptomycin (500 mug/ml) partially reverses the increase. These results suggest an interaction between strA mutations and recombination.
摘要
在含有链霉素抗性（strA）突变的大肠杆菌菌株中，染色体重复部分依赖重组的缺失比strA+亲本菌株高五到十倍。链霉素（500微克/毫升）可部分逆转这种增加。这些结果表明strA突变与重组之间存在相互作用。
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