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瘢痕疙瘩性痤疮广泛病例的手术治疗

The surgical management of extensive cases of acne keloidalis nuchae.

作者信息

Gloster H M

机构信息

Department of Dermatology, University of Cincinnati, 9275 Montgomery Rd, Suite 100, Cincinnati, OH 45242, USA.

出版信息

Arch Dermatol. 2000 Nov;136(11):1376-9. doi: 10.1001/archderm.136.11.1376.

DOI:10.1001/archderm.136.11.1376
PMID:11074701
Abstract

OBJECTIVE

To determine the efficacy of excision with primary closure in the treatment of extensive and refractory acne keloidalis nuchae (AKN).

DESIGN

Intervention before-after trial. Duration of follow-up ranged from 1 to 5 years.

SETTING

University-based ambulatory outpatient dermatologic surgery unit.

PATIENTS

Referred sample of 25 patients with extensive AKN that was refractory to medical management. All patients were healthy, young black men who had no medical problems and were not taking any medications. No other eligible patients refused to be included in the study. All 25 patients completed the study.

INTERVENTIONS

All 25 patients underwent surgical excision of AKN. Twenty of the 25 underwent excision with layered closure in 1 stage. Four patients underwent 2-stage excisions with layered closure. One patient underwent excision with second-intention healing.

MAIN OUTCOME MEASURE

A test of the following hypothesis: excision with primary closure is a successful treatment modality with little risk of recurrence for extensive cases of AKN.

RESULTS

The author and all 25 patients rated the cosmetic result of surgery as good to excellent. No patients experienced complete recurrence of their acne keloids. Fifteen patients developed tiny pustules and papules within the surgical scar. Five patients developed hypertrophic scars. Papules, pustules, and hypertrophic scars were all successfully treated with high-potency topical and intralesional steroids.

CONCLUSIONS

Excision with primary closure is an excellent surgical treatment modality for the management of extensive cases of AKN. Extremely large lesions should be excised in multiple stages. The surgeon should carefully assess each patient to determine whether AKN should be excised in 1 or multiple stages.

摘要

目的

确定一期切除缝合治疗广泛且难治性项部瘢痕疙瘩性痤疮(AKN)的疗效。

设计

前后对照干预试验。随访时间为1至5年。

地点

大学附属门诊皮肤科手术科室。

患者

选取25例经药物治疗无效的广泛AKN患者作为研究样本。所有患者均为健康年轻黑人男性,无其他疾病且未服用任何药物。无其他符合条件的患者拒绝纳入研究。25例患者均完成研究。

干预措施

25例患者均接受AKN手术切除。其中20例患者一期行分层缝合切除;4例患者分两期行分层缝合切除;1例患者行二期愈合切除。

主要观察指标

检验以下假设:一期切除缝合是治疗广泛型AKN的一种成功治疗方式,复发风险低。

结果

作者及所有25例患者均将手术美容效果评为良好至优秀。无患者瘢痕疙瘩完全复发。15例患者手术瘢痕内出现微小脓疱和丘疹。5例患者出现增生性瘢痕。丘疹、脓疱和增生性瘢痕均通过高效外用和皮损内注射类固醇成功治疗。

结论

一期切除缝合是治疗广泛型AKN的一种优秀手术治疗方式。极大的病变应分多期切除。外科医生应仔细评估每位患者,以确定AKN应一期还是多期切除。

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