Chhetri D K, Rawnsley J D, Calcaterra T C
Division of Head and Neck Surgery, UCLA School of Medicine, Los Angeles, CA 90095, USA.
Otolaryngol Head Neck Surg. 2000 Nov;123(5):566-71. doi: 10.1067/mhn.2000.110539.
The goal was to analyze the outcome of surgical therapy for buccal carcinoma.
A retrospective chart review was done.
The study took place in a major tertiary-care hospital.
Twenty-seven patients received first-time surgical therapy for buccal carcinoma. Treatment was surgery alone in 15 and surgery followed by radiation therapy in 6 patients. Six additional patients received surgical salvage for radiation therapy failure. Composite resection of the tumor was performed in 16 patients (59%). Five-year observed actuarial survival rates were 100%, 45%, 67%, and 78%, and locoregional recurrence rates were 0%, 27%, 44%, and 0% for stages I to IV, respectively. The 5-year actuarial survival rates were 80% after surgery and 82% after surgery and postoperative radiation therapy. Patients who underwent surgical salvage after radiation therapy failure had a 1-year survival rate of 0%.
Aggressive surgical treatment of buccal carcinoma may result in better survival rates.
The article analyzes buccal carcinoma in regards to the patterns of presentation, treatments rendered, and patterns of failure.
本研究旨在分析颊癌手术治疗的结果。
进行回顾性病历审查。
研究在一家大型三级医疗中心进行。
27例患者首次接受颊癌手术治疗。15例患者仅接受手术治疗，6例患者接受手术加放射治疗。另外6例患者因放射治疗失败接受挽救性手术。16例患者（59%）进行了肿瘤联合切除术。I至IV期患者的5年实际观察生存率分别为100%、45%、67%和78%，局部区域复发率分别为0%、27%、44%和0%。手术治疗后的5年实际生存率为80%，手术加术后放射治疗后的5年实际生存率为82%。放射治疗失败后接受挽救性手术的患者1年生存率为0%。
积极的颊癌手术治疗可能带来更好的生存率。
本文分析了颊癌的临床表现模式、所采用的治疗方法及失败模式。
