颊黏膜癌

Carcinoma of the buccal mucosa.

作者信息

Chhetri D K, Rawnsley J D, Calcaterra T C

机构信息

Division of Head and Neck Surgery, UCLA School of Medicine, Los Angeles, CA 90095, USA.

出版信息

Otolaryngol Head Neck Surg. 2000 Nov;123(5):566-71. doi: 10.1067/mhn.2000.110539.

DOI:10.1067/mhn.2000.110539

PMID:11077342

Abstract

OBJECTIVE

The goal was to analyze the outcome of surgical therapy for buccal carcinoma.

STUDY DESIGN

A retrospective chart review was done.

SETTING

The study took place in a major tertiary-care hospital.

RESULTS

Twenty-seven patients received first-time surgical therapy for buccal carcinoma. Treatment was surgery alone in 15 and surgery followed by radiation therapy in 6 patients. Six additional patients received surgical salvage for radiation therapy failure. Composite resection of the tumor was performed in 16 patients (59%). Five-year observed actuarial survival rates were 100%, 45%, 67%, and 78%, and locoregional recurrence rates were 0%, 27%, 44%, and 0% for stages I to IV, respectively. The 5-year actuarial survival rates were 80% after surgery and 82% after surgery and postoperative radiation therapy. Patients who underwent surgical salvage after radiation therapy failure had a 1-year survival rate of 0%.

CONCLUSION

Aggressive surgical treatment of buccal carcinoma may result in better survival rates.

SIGNIFICANCE

The article analyzes buccal carcinoma in regards to the patterns of presentation, treatments rendered, and patterns of failure.

摘要

目的

本研究旨在分析颊癌手术治疗的结果。

研究设计

进行回顾性病历审查。

研究地点

研究在一家大型三级医疗中心进行。

结果

27例患者首次接受颊癌手术治疗。15例患者仅接受手术治疗，6例患者接受手术加放射治疗。另外6例患者因放射治疗失败接受挽救性手术。16例患者（59%）进行了肿瘤联合切除术。I至IV期患者的5年实际观察生存率分别为100%、45%、67%和78%，局部区域复发率分别为0%、27%、44%和0%。手术治疗后的5年实际生存率为80%，手术加术后放射治疗后的5年实际生存率为82%。放射治疗失败后接受挽救性手术的患者1年生存率为0%。