Rubin R, Salvati E A, Lewis R
Oral Surg Oral Med Oral Pathol. 1976 Jan;41(1):18-23. doi: 10.1016/0030-4220(76)90247-4.
Three cases are reported in which there was a worrisome association between dental work and an infected total hip replacement. The patients had long asymptomatic intervals subsequent to implantation of prosthetic hip joints. After dental procedures, infections became apparent in these hips. Such infections carry an enormous and crippling morbidity. The potential complications of transient bacteremia in the patient with a cardiac valvular prosthesis are appreciated and the importance of prophylactic antibodies for dental work in such patients is well known. Although we emphasize that there is no proof that the infections in our patients were metastatic from the mouth, the sequence of events is suggestive. We recommend prophylactic antibiotics for dental work in the patient with a total hip replacement.
报告了三例牙科治疗与感染性全髋关节置换之间存在令人担忧关联的病例。患者在人工髋关节植入后有很长一段时间无症状。牙科治疗后，这些髋关节出现感染。此类感染会带来巨大且致残的发病率。心脏瓣膜假体患者发生短暂菌血症的潜在并发症是已知的，此类患者牙科治疗预防性使用抗生素的重要性也广为人知。尽管我们强调没有证据表明我们患者的感染是口腔转移性的，但事件发生顺序具有提示性。我们建议全髋关节置换患者在进行牙科治疗时预防性使用抗生素。
