Brinkhaus B, Lindner M, Schuppan D, Hahn E G
Department of Traditional and Complementary Medicine, Medical Department I, Friedrich-Alexander University, Erlangen-Nuremberg, Germany.
Phytomedicine. 2000 Oct;7(5):427-48. doi: 10.1016/s0944-7113(00)80065-3.
Centella asiatica is a medicinal plant that has been in use since prehistoric times. Its active constituents include pentacyclic triterpene derivatives. Studies have been conducted in particular to investigate the madecassosides and asiaticosides. In common with most traditional phytotherapeutic agents, Centella asiatica is used in folk medicine to treat a wide range of indications. In contrast to other medicinal plants, however, Centella asiatica has been subjected to quite extensive experimental and clinical investigations. Studies done in accordance with standardized scientific criteria have shown it to have a positive effect in the treatment of venous insufficiency and striae gravidarum. Centella asiatica also appears to be effective in the treatment of wound healing disturbances. At the present time, clinical studies aimed at investigating the sedative, analgesic, antidepressive, antimicrobial, antiviral and immunomodulatory effects that have been demonstrated experimentally, are still lacking. However, the therapeutic potential of this plant in terms of its efficacy and versatility is such that further detailed research would appear worthwhile.
积雪草是一种自史前时代就已被使用的药用植物。其活性成分包括五环三萜衍生物。人们已开展了多项研究，尤其对羟基积雪草苷和积雪草苷进行了调查。与大多数传统植物治疗剂一样，积雪草在民间医学中用于治疗多种病症。然而，与其他药用植物不同的是，积雪草已接受了相当广泛的实验和临床研究。按照标准化科学标准进行的研究表明，它在治疗静脉功能不全和妊娠纹方面具有积极作用。积雪草在治疗伤口愈合障碍方面似乎也有效。目前，旨在研究已在实验中得到证实的镇静、镇痛、抗抑郁、抗菌、抗病毒和免疫调节作用的临床研究仍然缺乏。然而，这种植物在功效和多功能性方面的治疗潜力使得进一步的详细研究似乎是值得的。
