积雪草在美容学中的应用。

Centella asiatica in cosmetology.

作者信息

Bylka Wiesława, Znajdek-Awiżeń Paulina, Studzińska-Sroka Elżbieta, Brzezińska Małgorzata

机构信息

Department of Pharmacognosy, Poznan University of Medical Sciences, Poland. Head: Prof. Irena Matławska.

出版信息

Postepy Dermatol Alergol. 2013 Feb;30(1):46-9. doi: 10.5114/pdia.2013.33378. Epub 2013 Feb 20.

Abstract

Centella asiatica known as Gotu Kola is a medicinal plant that has been used in folk medicine for hundreds of years as well as in scientifically oriented medicine. The active compounds include pentacyclic triterpenes, mainly asiaticoside, madecassoside, asiatic and madecassic acids. Centella asiatica is effective in improving treatment of small wounds, hypertrophic wounds as well as burns, psoriasis and scleroderma. The mechanism of action involves promoting fibroblast proliferation and increasing the synthesis of collagen and intracellular fibronectin content and also improvement of the tensile strength of newly formed skin as well as inhibiting the inflammatory phase of hypertrophic scars and keloids. Research results indicate that it can be used in the treatment of photoaging skin, cellulite and striae.

摘要

积雪草,又称雷公根,是一种药用植物,数百年来一直用于民间医学以及现代医学。其活性成分包括五环三萜类化合物,主要是积雪草苷、羟基积雪草苷、积雪草酸和羟基积雪草酸。积雪草对改善小伤口、增生性伤口以及烧伤、牛皮癣和硬皮病的治疗效果显著。其作用机制包括促进成纤维细胞增殖,增加胶原蛋白合成和细胞内纤连蛋白含量,提高新形成皮肤的抗张强度,以及抑制增生性瘢痕和瘢痕疙瘩的炎症期。研究结果表明,它可用于治疗光老化皮肤、脂肪团和妊娠纹。

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