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Intramuscular or intralipomatous injections?肌内注射还是脂肪内注射？
N Engl J Med. 1982 Aug 5;307(6):356-8. doi: 10.1056/NEJM198208053070607.

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Immunization with peptide encapsulated within synthetic spores activates T cell responses and reduces tumor growth.用包裹在合成孢子内的肽进行免疫可激活T细胞反应并减少肿瘤生长。
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本文引用的文献

1
Needle length and injection technique for efficient intramuscular vaccine delivery in infants and children evaluated through an ultrasonographic determination of subcutaneous and muscle layer thickness.通过超声测定皮下和肌肉层厚度评估婴幼儿高效肌内注射疫苗的针头长度和注射技术。
Pediatrics. 1997 Sep;100(3 Pt 1):400-3. doi: 10.1542/peds.100.3.400.
2
Determination of deltoid fat pad thickness. Implications for needle length in adult immunization.三角肌脂肪垫厚度的测定。对成人免疫接种中针头长度的影响。
JAMA. 1997 Jun 4;277(21):1709-11.
3
General recommendations on immunization. Recommendations of the Advisory Committee on Immunization Practices (ACIP).免疫接种的一般建议。免疫实践咨询委员会（ACIP）的建议。
MMWR Recomm Rep. 1994 Jan 28;43(RR-1):1-38.
4
Injection granulomas. Intramuscle or intrafat?
Arch Fam Med. 1994 Feb;3(2):146-8. doi: 10.1001/archfami.3.2.146.
5
Injection granuloma of the buttock.臀部注射性肉芽肿
Can Med Assoc J. 1970 Mar 28;102(6):626-8.
6
Adverse reactions to diphtheria, tetanus, pertussis-polio vaccination at 18 months of age: effect of injection site and needle length.18月龄时白喉、破伤风、百日咳-脊髓灰质炎疫苗接种的不良反应：注射部位和针头长度的影响
Pediatrics. 1989 May;83(5):679-82.
7
Effect of anatomic injection site, age and smoking on the immune response to hepatitis B vaccination.
Vaccine. 1989 Oct;7(5):425-30. doi: 10.1016/0264-410x(89)90157-6.
8
Intramuscular injection of drugs.
N Engl J Med. 1976 Sep 2;295(10):542-6. doi: 10.1056/NEJM197609022951006.
9
Intramuscular injection-site complications.肌内注射部位并发症。
JAMA. 1978 Aug 11;240(6):542-4.

The importance of injecting vaccines into muscle. Different patients need different needle sizes.

作者信息

Zuckerman J N

出版信息

BMJ. 2000 Nov 18;321(7271):1237-8. doi: 10.1136/bmj.321.7271.1237.

DOI:10.1136/bmj.321.7271.1237
PMID:11082069
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1118997/
Abstract
摘要