细胞骨架：微管蛋白修饰功能终得揭示。
Cytoskeleton: functions for tubulin modifications at last.
作者信息
Rosenbaum J
机构信息
Department of Biology, Yale University, 310 Kline Biology Tower, New Haven, Connecticut 06511-8112, USA.
出版信息
Curr Biol. 2000 Nov 2;10(21):R801-3. doi: 10.1016/s0960-9822(00)00767-3.
Abstract
New studies show that three types of evolutionarily conserved post translational tubulin modification, polyglutamylation, polyglycylation and detyrosination, play important roles in vivo. These modifications appear to act by modulating the binding of molecular motors to the external surface of microtubules.
摘要
新的研究表明，三种进化上保守的微管蛋白翻译后修饰，即多聚谷氨酰胺化、多聚甘氨酰胺化和去酪氨酸化，在体内发挥着重要作用。这些修饰似乎是通过调节分子马达与微管外表面的结合来起作用的。
Zotero 插件