Gayko G, Cholcha W, Kietzmann M
Ichthyol-Gesellschaft, Hamburg.
Berl Munch Tierarztl Wochenschr. 2000 Oct;113(10):368-73.
Dark sulfonated shale oil (Ichthammol, ammoniumbituminosulfonate) is an active ingredient of natural origin that was included in Annex II of European Council Regulation (EEC) 2377/90. Therefore, this well-tolerated substance is available further on as a dermatological agent for the application to animals from which food is produced for human consumption. The manifold pharmacological actions could be substantiated in numerous in-vitro studies using the Ichthammol from Seefeld, Austria. The antiinflammatory action which is well-known from clinical experience could be traced back to an influence of the substance on the formation, secretion and effect of inflammation mediators. Antibacterial and antimycotic actions which are well-known from clinical use could be confirmed in in-vitro studies as well.
深色磺化页岩油（鱼石脂，氨沥青磺酸盐）是一种天然来源的活性成分，已被列入欧洲理事会条例（EEC）2377/90的附件II。因此，这种耐受性良好的物质可作为皮肤科用药，用于生产供人类食用的动物食品。使用来自奥地利塞费尔德的鱼石脂进行的大量体外研究证实了其多种药理作用。临床经验中熟知的抗炎作用可追溯到该物质对炎症介质形成、分泌和作用的影响。临床应用中熟知的抗菌和抗真菌作用也在体外研究中得到了证实。
