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用丙缩羟强龙联合季铵盐治疗脓疱化湿疹

[Treatment of impetiginized eczema with prednicarbate in combination with a quarternary ammonium salt].

作者信息

Wölbling R H, Schäfer V

出版信息

Arzneimittelforschung. 1987 Feb;37(2):218-20.

PMID:3555513
Abstract

After a brief account of the therapeutic problems with microbially superinfected eczemas, the results of a double-blind study of hospitalized patients are reported. Two concentrations of the antibacterial agent Bardac-22 (didecyl-dimethyl-ammonium chloride. Hoe S 2922) in combination with the steroid prednicarbate (prednisolone 17-(ethylcarbonate)-21-propionate, Hoe 777) were used. The quantitative determination of cutaneous bacteria was performed by a modified method of Faergemann. The double blind study did not reveal any significant differences in effectiveness, although a trend in favour of the higher concentration was apparent.

摘要

在简要阐述微生物二重感染性湿疹的治疗问题后,报告了一项针对住院患者的双盲研究结果。使用了两种浓度的抗菌剂Bardac - 22(二癸基二甲基氯化铵,Hoe S 2922)与类固醇泼尼松卡酯(泼尼松龙17 -(碳酸乙酯)- 21 - 丙酸酯,Hoe 777)联合使用。采用改良的费格曼方法对皮肤细菌进行定量测定。双盲研究未发现有效性方面有任何显著差异,尽管存在有利于较高浓度的趋势。

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