Wölbling R H, Schäfer V
Arzneimittelforschung. 1987 Feb;37(2):218-20.
After a brief account of the therapeutic problems with microbially superinfected eczemas, the results of a double-blind study of hospitalized patients are reported. Two concentrations of the antibacterial agent Bardac-22 (didecyl-dimethyl-ammonium chloride. Hoe S 2922) in combination with the steroid prednicarbate (prednisolone 17-(ethylcarbonate)-21-propionate, Hoe 777) were used. The quantitative determination of cutaneous bacteria was performed by a modified method of Faergemann. The double blind study did not reveal any significant differences in effectiveness, although a trend in favour of the higher concentration was apparent.
在简要阐述微生物二重感染性湿疹的治疗问题后，报告了一项针对住院患者的双盲研究结果。使用了两种浓度的抗菌剂Bardac - 22（二癸基二甲基氯化铵，Hoe S 2922）与类固醇泼尼松卡酯（泼尼松龙17 -（碳酸乙酯）- 21 - 丙酸酯，Hoe 777）联合使用。采用改良的费格曼方法对皮肤细菌进行定量测定。双盲研究未发现有效性方面有任何显著差异，尽管存在有利于较高浓度的趋势。
