Drobyshevskaia E I, Kiseleva B S, Golubeva I V, Ratiner Iu A, Ershov A A
Zh Mikrobiol Epidemiol Immunobiol. 1975 May(5):44-8.
A study was made of 155 strains of E. coli of the O4 serological group isolated from sick children and adults during group and sporadic acute intestinal diseases), from persons who came in contact with them, and also from healthy persons during prophylactic examination; three standard cultures were examined as well. Along with strains with a typical enzymatic activity there were strains which produced retarded lactose fermentation and also gas-free, immobile and lysin-negative strains resembling Shigellae. Eight biochemical types were determined among E. coli 04. A study of the antigenic structure by cross agglutinin adsorption indicated identicity of the strains by O-antigen and their difference by the K- and H-antigens. Circulation of E. coli of serological types O4: K12(L): H1,O4: K3(L): H5,O4: K3(L): H12,04: K12(L): H40,04: K52(L): H4, and O4: K12(L) HII was revealed; the first two serological types prevailed. Serological types of O4: K3(L):H12, O4: K12(L): HI and O4: K12(L): H40, isolated in cases of group and sporadic acute intestinal diseases were described for the first time.
对从患急性肠道疾病（包括群体性和散发性）的儿童和成人、与之接触者以及预防性检查期间的健康人身上分离出的155株O4血清群大肠杆菌进行了研究；还检查了三种标准培养物。除了具有典型酶活性的菌株外，还有乳糖发酵迟缓的菌株，以及无气体、不运动和溶菌素阴性的类似志贺氏菌的菌株。在大肠杆菌O4中确定了八种生化类型。通过交叉凝集素吸附对抗原结构进行的研究表明，这些菌株的O抗原相同，而K抗原和H抗原不同。发现了血清型为O4:K12(L):H1、O4:K3(L):H5、O4:K3(L):H12、O4:K12(L):H40、O4:K52(L):H4和O4:K12(L):HII的大肠杆菌在传播；前两种血清型占主导。首次描述了在群体性和散发性急性肠道疾病病例中分离出的O4:K3(L):H12、O4:K12(L):H1和O4:K12(L):H40血清型。
