Kiseleva B S, Gedze G I, Drobyshevskaia E I, Chuprun R M, Kireeva L M
Zh Mikrobiol Epidemiol Immunobiol. 1976 Jun(6):70-3.
The authors present the results of studies of etiology of acute group intestinal diseases in neonates from whom escherichia of serological group 0128ac:K67 possessing the following characteristics were isolated: of the same (with the H12 antigen) serological and enzymatic type (nonfermenting sucrose and raffinose, fermenting dulcit and sorbit the first 24 hours, and slowly fermenting ramnose). All the cultures isolated were resistant to the majority of antibiotics used at present, and were only weakly sensitive to erythromycin. Difficulties (agglutination of live cultures with production sera in the absence of low agglutinability of heated cultures) in serological typing of the cultures were due to different partial O-antigen composition of the cultures isolated and of the production strain used in the preparation of commercial sera of the given serological group (0128ab:K67). Because circulation of escherichia of serological 0128ac variant was revealed in the USSR there occurred a necessity of their identification in practical laboratories; for this purpose organization of industrial production of the corresponding serum is necessary.
作者介绍了对新生儿急性肠道疾病病因学研究的结果,从这些新生儿中分离出了血清群0128ac:K67的大肠杆菌,其具有以下特征:属于相同的(具有H12抗原)血清学和酶学类型(不发酵蔗糖和棉子糖,在最初24小时发酵卫矛醇和山梨醇,并缓慢发酵鼠李糖)。所有分离出的培养物对目前使用的大多数抗生素具有抗性,仅对红霉素敏感。培养物血清学分型困难(活菌培养物与效价血清发生凝集,而加热培养物无低凝集性)是由于分离出的培养物和用于制备给定血清群(0128ab:K67)商业血清的生产菌株的部分O抗原组成不同。由于在苏联发现了血清型0128ac变体大肠杆菌的传播,因此有必要在实际实验室中对其进行鉴定;为此,必须组织相应血清的工业化生产。