Nakamura H, Ito N, Kotake F, Mizokami Y, Matsuoka T
Fifth Department of Internal Medicine, Tokyo Medical University Kasumigaura Hospital, Ibaraki, Japan.
J Gastroenterol. 2000;35(11):849-55. doi: 10.1007/s005350070022.
The tumor-detecting capacity and clinical usefulness of superparamagnetic iron oxide (SPIO) magnetic resonance imaging (MRI) were examined in patients with hepatocellular carcinoma. The tumor detection rate of SPIO-MRI (64.5%) was comparable to those of dynamic computed tomography (CT) and plain MRI, but lower than that for Gd dynamic MRI (93.5%; P < 0.01%). A combination of Gd dynamic MRI and SPIO-MRI improved the detection rate; further, the tumor stage with respect to tumor blood-flow pattern was predicted by combining plain MRI with SPIO-MRI. This combination procedure may also be useful for selecting therapeutic strategies.
对肝细胞癌患者检测了超顺磁性氧化铁（SPIO）磁共振成像（MRI）的肿瘤检测能力和临床实用性。SPIO-MRI的肿瘤检测率（64.5%）与动态计算机断层扫描（CT）和平扫MRI相当，但低于钆动态MRI（93.5%；P<0.01%）。钆动态MRI和SPIO-MRI联合使用可提高检测率；此外，通过平扫MRI与SPIO-MRI联合使用可预测肿瘤血流模式相关的肿瘤分期。这种联合方法可能对选择治疗策略也有用。
