Renck H, Edström H
Acta Anaesthesiol Scand Suppl. 1975;57:89-97. doi: 10.1111/j.1399-6576.1975.tb05418.x.
A double-blind comparison was made in 40 patients undergoing thoracic epidural analgesia with either bupivacaine 0.5% or etidocaine 1.0%, both with adrenaline 5 mug/ml. All patients were undergoing elective upper abdominal surgery. They were studied both pre- and postoperatively. The parameters measured were: onset time, segmental spread and duration of analgesia; and also systolic blood pressure, heart rate and peak expiratory flow rate. In respect of these parameters, no major differences were found between the two solutions under the conditions of the study. The overall results, however, differ in many respects to those found when these agents are used in lumbar epidural analgesia.
对40例接受胸段硬膜外镇痛的患者进行了双盲比较，分别使用0.5%布比卡因或1.0%依替卡因，两者均添加5μg/ml肾上腺素。所有患者均接受择期上腹部手术。对他们在术前和术后都进行了研究。测量的参数包括：镇痛起效时间、节段性扩散和持续时间；以及收缩压、心率和呼气峰值流速。在本研究条件下，两种溶液在这些参数方面未发现重大差异。然而，总体结果在许多方面与这些药物用于腰段硬膜外镇痛时的结果不同。
