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1
Measurement of endotoxins with the limulus test in burned patients.用鲎试剂法检测烧伤患者内毒素
J Hyg (Lond). 1979 Aug;83(1):151-6. doi: 10.1017/s0022172400025924.
2
Detection of endotoxins with the Limulus test in burned and unburned mice infected with different species of gram-negative bacteria.用鲎试剂法检测感染不同种类革兰氏阴性菌的烧伤和未烧伤小鼠体内的内毒素。
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3
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4
[Determination of blood endotoxin in severely burned patients and its clinical significance].
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Principles of a quantitative assay for bacterial endotoxins in blood that uses Limulus lysate and a chromogenic substrate.一种使用鲎试剂和显色底物对血液中细菌内毒素进行定量测定的方法的原理。
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4
The gut as a portal of entry for bacteremia. Role of protein malnutrition.肠道作为菌血症的一个入口途径。蛋白质营养不良的作用。
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5
Inhibition of endotoxin-induced bacterial translocation in mice.对内毒素诱导的小鼠细菌移位的抑制作用。
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本文引用的文献

1
Picogram-sensitive assay for endotoxin: gelation of Limulus polyphemus blood cell lysate induced by purified lipopolysaccharides and lipid A from Gram-negative bacteria.内毒素的皮克级灵敏检测法:革兰氏阴性菌纯化脂多糖和脂质A诱导鲎血细胞溶解物凝胶化。
Biochim Biophys Acta. 1972 Jan 28;261(1):284-9. doi: 10.1016/0304-4165(72)90340-6.
2
Gram-negative bacilli in burns.烧伤中的革兰氏阴性杆菌
J Clin Pathol. 1969 Nov;22(6):634-41. doi: 10.1136/jcp.22.6.634.
3
Endotoxaemia in man.人类内毒素血症
Lancet. 1972 Jun 24;1(7765):1381-5. doi: 10.1016/s0140-6736(72)91108-7.
4
A new Pseudomonas vaccine: preliminary trial on human volunteers.一种新型假单胞菌疫苗:人体志愿者初步试验
J Hyg (Lond). 1976 Jun;76(3):429-39. doi: 10.1017/s0022172400055364.
5
Detection of endotoxins with the Limulus test in burned and unburned mice infected with different species of gram-negative bacteria.用鲎试剂法检测感染不同种类革兰氏阴性菌的烧伤和未烧伤小鼠体内的内毒素。
J Hyg (Lond). 1975 Aug;75(1):99-112. doi: 10.1017/s0022172400047112.
6
A new polyvalent Pseudomonas vaccine.一种新型多价假单胞菌疫苗。
J Med Microbiol. 1977 Feb;10(1):19-27. doi: 10.1099/00222615-10-1-19.
7
Low mortality in burned patients in a Pseudomonas vaccine trial.在一项铜绿假单胞菌疫苗试验中烧伤患者的低死亡率
Lancet. 1978 Aug 19;2(8086):401-3. doi: 10.1016/s0140-6736(78)91868-8.
8
Does endotoxin cause both the disease and parasite death in acute malaria and babesiosis?内毒素会导致急性疟疾和巴贝斯虫病中的疾病发生以及寄生虫死亡吗?
Lancet. 1978 Jul 8;2(8080):75-7. doi: 10.1016/s0140-6736(78)91386-7.

用鲎试剂法检测烧伤患者内毒素

Measurement of endotoxins with the limulus test in burned patients.

作者信息

Jones R J, Roe E A

出版信息

J Hyg (Lond). 1979 Aug;83(1):151-6. doi: 10.1017/s0022172400025924.

DOI:10.1017/s0022172400025924
PMID:110875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2130093/
Abstract

High titres of endotoxin as measured by the Limulus test were usually found in burned patients who had raised body temperatures, and were colonized with gram-negative bacteria; also some infected patients showed raised endotoxin without a raised temperature. Patients vaccinated with an antipseudomonas vaccine rarely showed endotoxin in their plasma but occasional plasma samples from vaccinated patients had a high titre of endotoxin which appeared unrelated to infection or to a raised temperature in the patient.

摘要

通过鲎试剂检测发现,体温升高且被革兰氏阴性菌定植的烧伤患者体内通常存在高滴度内毒素;此外,一些感染患者体温未升高但内毒素水平升高。接种抗假单胞菌疫苗的患者血浆中很少出现内毒素,但接种疫苗患者的偶尔几份血浆样本中内毒素滴度较高,这似乎与感染或患者体温升高无关。