Cesario T, Jason M, Andrews B S, Shanbron E, Juranas D, Katz L, Friou G J
Ann Rheum Dis. 1983 Oct;42(5):571-4. doi: 10.1136/ard.42.5.571.
The limulus assay for the detection of bacterial endotoxin has been applied to the study of synovial fluid. Three of 5 patients (60%) with culture-positive gonococcal arthritis had positive SF limulus assay results; as did 2 of 11 (18%) with presumptive evidence of gonococcal arthritis, 3 of 6 (50%) with nongonococcal infectious arthritis, and none of 47 patients with noninfectious arthritis. Endotoxin levels ranged from 0.25 to 128.0 ng/ml. As at present applied to synovial fluid the commercial limulus assay appears to be specific for the infectious process but apparently lacks sensitivity.
鲎试剂检测细菌内毒素的方法已应用于滑液研究。5例培养阳性的淋菌性关节炎患者中有3例（60%）滑液鲎试剂检测结果为阳性；11例疑似淋菌性关节炎患者中有2例（18%）、6例非淋菌性感染性关节炎患者中有3例（50%）检测结果为阳性，而47例非感染性关节炎患者检测结果均为阴性。内毒素水平在0.25至128.0 ng/ml之间。目前应用于滑液检测时，市售鲎试剂检测法似乎对感染过程具有特异性，但显然缺乏敏感性。
