Sanfey H, Aguilar M, Jones R S
Department of Surgery, University of Virginia Health Sciences Center, Charlottesville.
Am Surg. 1994 Sep;60(9):661-8.
Pseudocysts represent a relatively common problem in the management of patients with pancreatic disease. In evaluating the outcome of treatment, many authors have failed to differentiate between those pseudocysts that follow an attack of acute pancreatitis and those that occur with established chronic disease. We retrospectively reviewed the outcome of treatment in 97 patients admitted to the University of Virginia Hospital in Charlottesville over a 6-year period with a diagnosis of pancreatitis pseudocyst. In 50 of the 97 patients (52%), the pancreatic pseudocyst followed an attack of acute pancreatitis, and 47 (48%) patients had chronic disease. The mean age at presentation was 48.6 +/- 16.4 years for the entire group. Twenty-four patients (25%) were black, and 73 (75%) were white. Sixty-four patients were male (66%), and 33 were female (34%). Alcohol was the important etiological agent in 30 of the 47 patients with chronic pancreatitis (64%), but only 13 of the 50 patients (26%) with acute pancreatitis. By comparison, gallstones were the precipitating cause in 13 of the 50 patients with acute pancreatitis (26%), but only 5 of the 47 patients (11%) with chronic pancreatitis. Thirty-one patients (32%) were treated by observation, 37 patients (36%) by percutaneous aspiration or drainage, and 46 patients (47%) by surgical drainage or resection. Some patients fell into more than one category. Our findings suggested that many patients with small cysts (less than 6 cm) can be managed by a period of observation.(ABSTRACT TRUNCATED AT 250 WORDS)
假性囊肿是胰腺疾病患者治疗中较为常见的问题。在评估治疗效果时,许多作者未能区分急性胰腺炎发作后出现的假性囊肿和已确诊的慢性疾病伴发的假性囊肿。我们回顾性分析了夏洛茨维尔弗吉尼亚大学医院6年间收治的97例诊断为胰腺炎假性囊肿患者的治疗结果。97例患者中,50例(52%)的胰腺假性囊肿继发于急性胰腺炎发作,47例(48%)患者患有慢性疾病。整个组患者就诊时的平均年龄为48.6±16.4岁。24例患者(25%)为黑人,73例(75%)为白人。64例患者为男性(66%),33例为女性(34%)。酒精是47例慢性胰腺炎患者中30例(64%)的重要病因,但在50例急性胰腺炎患者中仅13例(26%)是病因。相比之下,胆结石是50例急性胰腺炎患者中13例(26%)的诱发原因,但在47例慢性胰腺炎患者中仅5例(11%)是诱发原因。31例患者(32%)接受观察治疗,37例患者(36%)接受经皮抽吸或引流治疗,46例患者(47%)接受手术引流或切除治疗。部分患者归入不止一类治疗方式。我们的研究结果表明,许多小囊肿(小于6厘米)患者可通过一段时间的观察进行处理。(摘要截选至250字)