Laml T, Hartmann B W, Kirchengast S, Preyer O, Albrecht A E, Husslein P W
Department of Obstetrics and Gynecology, University of Vienna Medical School, Vienna, Austria.
Gynecol Obstet Invest. 2000;50(4):231-6. doi: 10.1159/000010322.
The purpose of this study was to determine the effect of maternal pre-pregnancy body mass index (BMI) and maternal smoking habits on neonatal birth weight. We reviewed 10,240 normal singleton term pregnancies between 1985 and 1995 at the University Department of Obstetrics and Gynecology, Vienna. Birth weights of infants of overweight smokers were greater than those of smokers in general and similar to birth weights of nonsmokers, but smoking did have a fetal growth-retarding effect in overweight smoking mothers. Infants of underweight mothers who increased their daily cigarette consumption during pregnancy had significantly lowest birth weight. Our results suggest that the negative effects of smoking during pregnancy cannot be mitigated by a higher pre-pregnancy BMI and/or an improved weight gain during pregnancy. Especially the infants of underweight mothers benefit from their mothers' decision to cease smoking.
本研究的目的是确定孕前体重指数（BMI）和孕妇吸烟习惯对新生儿出生体重的影响。我们回顾了1985年至1995年间维也纳大学妇产科的10240例正常单胎足月妊娠。超重吸烟者所生婴儿的出生体重高于一般吸烟者，与非吸烟者的出生体重相似，但吸烟对超重吸烟母亲的胎儿生长有迟缓作用。孕期每日吸烟量增加的体重过轻母亲所生婴儿的出生体重显著最低。我们的结果表明，孕期吸烟的负面影响不会因较高的孕前BMI和/或孕期体重增加改善而减轻。尤其是体重过轻母亲所生的婴儿，受益于其母亲戒烟的决定。
