Godfrey D I, Hammond K J, Poulton L D, Smyth M J, Baxter A G
Dept of Pathology and Immunology, Monash University Medical School, Commercial Road, VIC. 3181, Prahran, Australia.
Immunol Today. 2000 Nov;21(11):573-83. doi: 10.1016/s0167-5699(00)01735-7.
The proposed roles of NK1.1(+) T (NKT) cells in immune responses range from suppression of autoimmunity to tumor rejection. Heterogeneity of these cells contributes to the controversy surrounding their development and function. This review aims to provide an update on NKT cell biology and, whenever possible, to compare what is known about NKT-cell subsets.
自然杀伤细胞1.1（NK1.1）阳性T（NKT）细胞在免疫反应中所发挥的作用，涵盖了从抑制自身免疫到肿瘤排斥等多个方面。这些细胞的异质性导致了围绕其发育和功能的争议。本综述旨在提供NKT细胞生物学的最新进展，并尽可能比较关于NKT细胞亚群的已知信息。
