Little M A, Conlon P J, Walshe J J
Department of Nephrology and Renal Transplantation, Beaumont Hospital, Dublin, Ireland.
Am J Kidney Dis. 2000 Dec;36(6):1135-9. doi: 10.1053/ajkd.2000.19821.
Ultrasound dilution technology is emerging as the standard for measuring access recirculation and blood flow in hemodialysis patients. In temporary dialysis catheters, studies using the traditional two-needle urea method have suggested that short femoral catheters are associated with an unacceptably high degree of recirculation. This problem has never been assessed using ultrasound dilution technology. We performed a prospective observational study of consecutive patients undergoing dialysis through a temporary catheter. Measurements were made on 49 catheters; 10 catheters were excluded because poor flow necessitated reversal of the dialysis ports. Thirty-nine catheters in 33 patients were included in this analysis, of which 26 catheters were located in the femoral vein, and 13 catheters, in the internal jugular vein. Dialyzer blood flow was adjusted to give an ultrasonic flow rate of 250 mL/min (actual mean blood flow, 234.3 mL/min; 95% confidence interval [CI], 228 to 241). Overall mean recirculation rate was 8.9% (95% CI, 4.8 to 13.0). Multivariate analysis showed catheter location and length to be independent predictors of recirculation. Blood flow (within the range tested), duration into dialysis, time since catheter insertion, cardiac rhythm, and catheter type had no significant effect on recirculation rates. Recirculation in femoral catheters (13.1%) was significantly greater than that in internal jugular catheters (0.4%; P: < 0.001). Femoral catheters shorter than 20 cm had significantly greater recirculation (26.3%) than those longer than 20 cm (8.3%; P: = 0.007). We conclude that temporary femoral catheters shorter than 20 cm are associated with increased recirculation rates. In addition, when dialysis dose delivery is a priority, locating the temporary catheter in the internal jugular vein is an advantage.
超声稀释技术正逐渐成为测量血液透析患者血管通路再循环和血流量的标准方法。在临时透析导管方面,使用传统双针尿素法的研究表明,股静脉短导管的再循环程度高得令人难以接受。而这一问题从未使用超声稀释技术进行评估。我们对连续通过临时导管进行透析的患者进行了一项前瞻性观察研究。对49根导管进行了测量;10根导管因血流量不佳需要更换透析端口而被排除。本分析纳入了33例患者的39根导管,其中26根导管位于股静脉,13根导管位于颈内静脉。将透析器血流量调整为使超声流速达到250 mL/分钟(实际平均血流量为234.3 mL/分钟;95%置信区间[CI],228至241)。总体平均再循环率为8.9%(95%CI,4.8至13.0)。多因素分析显示导管位置和长度是再循环的独立预测因素。血流量(在所测试的范围内)入透析时间、导管插入后的时间、心律和导管类型对再循环率没有显著影响。股静脉导管的再循环率(13.1%)显著高于颈内静脉导管(0.4%;P:<0.001)。长度小于20 cm的股静脉导管的再循环率(26.3%)显著高于长度大于20 cm的股静脉导管(8.3%;P:=0.007)。我们得出结论,长度小于20 cm的临时股静脉导管与再循环率增加有关。此外,当优先考虑透析剂量输送时,将临时导管置于颈内静脉是一个优势。