Schwartz JS
Department of Medicine, Buffalo General Hospital, 100 High Street, Buffalo, NY 14203, USA.
Curr Treat Options Cardiovasc Med. 2000 Feb;2(1):27-36. doi: 10.1007/s11936-000-0026-x.
The goals of treatment of ischemic heart disease are to relieve symptoms, prevent unstable angina or myocardial infarction, and prolong life. Over the past four decades, significant advances in therapy have occurred, initially involving revascularization procedures. Although coronary bypass surgery and percutaneous catheter-based interventions continue to play an important role in therapy, appropriate medical therapy has been shown to have a major impact on the course of the disease and can decrease the need for revascularization. Lifestyle changes (eg, cessation of smoking) and pharmacologic therapy (eg, the use of aspirin, beta-blockers, and lipid-lowering agents) have been shown to decrease the occurrence of acute ischemic events and to prolong life in patients with coronary disease. Although it is likely that new therapies will emerge as our understanding of the basic mechanism of atherosclerosis increases, it is important to be sure that current medical therapy is provided to all appropriate patients.
缺血性心脏病的治疗目标是缓解症状、预防不稳定型心绞痛或心肌梗死并延长寿命。在过去的四十年里，治疗方面取得了重大进展，最初涉及血运重建手术。尽管冠状动脉搭桥手术和经皮导管介入治疗在治疗中继续发挥重要作用，但适当的药物治疗已被证明对疾病进程有重大影响，并且可以减少血运重建的需求。生活方式改变（如戒烟）和药物治疗（如使用阿司匹林、β受体阻滞剂和降脂药物）已被证明可减少急性缺血事件的发生并延长冠心病患者的寿命。尽管随着我们对动脉粥样硬化基本机制的理解不断深入，可能会出现新的治疗方法，但确保向所有合适的患者提供当前的药物治疗非常重要。
