Svartvik L, Lidfeldt J, Nerbrand C, Samsioe G, Scherstén B, Nilsson P M
Department of Community Medicine, University of Lund, Sweden.
Scand J Prim Health Care. 2000 Sep;18(3):177-82. doi: 10.1080/028134300453395.
A low Sense of Coherence (SOC) is a concept related to a feeling of ill health. Not much is known about possible relationships between SOC and biological factors.
Population-based study of middle-aged women.
Four-hundred-and-fifty women participated as a subgroup of a larger study of cardiovascular risk factor screening. A self-administered questionnaire with 29 questions related to SOC was completed in addition to questions on social background factors and medical history.
The mean score of SOC was 150.9 (SD 23.4). HDL cholesterol was lower (p < 0.05) and triglyceride levels higher (p < 0.05) in women with low SOC (1.5 and 2.1 mmol/L) compared to women with medium (1.8 and 1.4 mmol/L) or high SOC (1.7 and 1.5 mmol/L). In multiple regression analysis, a low HDL cholesterol level was still significantly associated with low SOC (p < 0.05) after adjustment for possible confounders. Women reporting low SOC were further characterised by a higher proportion of subjects with regular clinical visits for health care (49% vs 35% and 29%).
Middle-aged women reporting low SOC showed lower HDL cholesterol and higher triglyceride levels, and reported more clinical visits and medical symptoms than women with higher SOC.
低连贯感(SOC)是一个与健康不佳感受相关的概念。关于SOC与生物因素之间可能存在的关系,目前所知甚少。
基于人群的中年女性研究。
450名女性作为一项更大规模心血管危险因素筛查研究的子组参与研究。除了关于社会背景因素和病史的问题外,还完成了一份包含29个与SOC相关问题 的自填式问卷。
SOC的平均得分为150.9(标准差23.4)。与SOC中等(1.8和1.4 mmol/L)或较高(1.7和1.5 mmol/L)的女性相比,SOC较低的女性(1.5和2.1 mmol/L)的高密度脂蛋白胆固醇较低(p<0.05),甘油三酯水平较高(p<0.05)。在多元回归分析中,在对可能的混杂因素进行调整后,低高密度脂蛋白胆固醇水平仍与低SOC显著相关(p<0.05)。报告SOC较低的女性的另一个特征是定期进行医疗保健临床就诊的受试者比例更高(49%,而其他组分别为35%和29%)。
报告SOC较低的中年女性的高密度脂蛋白胆固醇较低,甘油三酯水平较高,且与SOC较高的女性相比,她们报告的临床就诊次数更多,症状更多。