Stensvold Einar, Magelssen Henriette, Oskam Irma C
Clinic for Children and Adolescents, Akershus University Hospital, Norway.
Tidsskr Nor Laegeforen. 2011 Aug 9;131(15):1433-5. doi: 10.4045/tidsskr.11.0426.
Some types of cancer treatment entail a risk of reduced fertility and infertility. Fertility-preserving treatment can reduce the risk for some. The purpose of this article is to provide an overview of the risk of infertility after treatment of boys and young men with cancer and of fertility-preserving measures.
The article is based on literature searches in the medical databases Medline, Pubmed and Scopus and on the experience of a Nordic medical network collaboration.
Cryopreservation of sperm is an established method for adult cancer patients in Norway. Vibratory stimulation of the penis and electroejaculation with subsequent freezing of sperm may be an option for young cancer patients who cannot manage to produce a semen sample with the aid of masturbation. Freezing of testicular biopsies may be an option for prepubertal boys who are not capable of producing mature sperm.
There are established methods for cryopreservation of sperm for adult cancer patients. The other fertility-preserving measures for boys and young men with cancer are regarded as experimental at present.
某些类型的癌症治疗存在生育能力下降和不育的风险。生育力保存治疗可以降低部分患者的这种风险。本文旨在概述癌症男童和青年男性治疗后不育的风险以及生育力保存措施。
本文基于对医学数据库Medline、Pubmed和Scopus的文献检索以及北欧医学网络合作的经验。
在挪威，精子冷冻保存是成年癌症患者的一种既定方法。对于无法通过手淫获取精液样本的年轻癌症患者，阴茎振动刺激和电射精随后冷冻精子可能是一种选择。对于不能产生成熟精子的青春期前男孩，冷冻睾丸活检组织可能是一种选择。
成年癌症患者的精子冷冻保存已有既定方法。目前，针对癌症男童和青年男性的其他生育力保存措施被视为试验性的。
