Golden R N, Nicholas L
Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill 27599-7160, USA.
Depress Anxiety. 2000;12 Suppl 1:45-9. doi: 10.1002/1520-6394(2000)12:1+<45::AID-DA5>3.0.CO;2-5.
Venlafaxine is a unique antidepressant medication with well documented efficacy and safety in the acute treatment of major depressive disorder. Reports suggest that it may also be effective in the treatment of dysthymic disorder and bipolar II depression, but the available data for these conditions are more limited compared to major depressive disorder. Several studies suggest that there may be a more rapid onset of action for venlafaxine in the treatment of major depression compared to other antidepressant pharmacotherapies, but this has not been fully established. Venlafaxine is also effective in the important long term continuation and maintenance phases of the treatment of depression.
文拉法辛是一种独特的抗抑郁药物，在重度抑郁症的急性治疗中，其疗效和安全性都有充分的文献记载。报告表明，它在治疗恶劣心境障碍和双相II型抑郁症方面可能也有效，但与重度抑郁症相比，针对这些病症的现有数据更为有限。几项研究表明，与其他抗抑郁药物疗法相比，文拉法辛在治疗重度抑郁症时可能起效更快，但这一点尚未完全得到证实。文拉法辛在抑郁症治疗的重要长期延续和维持阶段也同样有效。
