基质周转

Matrix turnover.

作者信息

Kerrigan J J, Mansell J P, Sandy J R

机构信息

Division of Child Dental Health, University of Bristol Dental School, Lower Maudlin Street, Bristol BS1 2LY, UK.

出版信息

J Orthod. 2000 Sep;27(3):227-33. doi: 10.1179/ortho.27.3.227.

DOI:10.1179/ortho.27.3.227

PMID:11099555

Abstract

This review concentrates on how the major component of extracellular matrix, collagen, is catabolized. This process is important in a number of aspects of orthodontics since matrix is constantly turning over, the rate of which differs in embryogenesis, ageing, disease, and physiological processes, such as orthodontic tooth movement. It is not the purpose of this review to consider each process in detail. The aim is to give a clear account of the matrix metalloproteinases (a major family of proteinases) including their classification, properties, and functions.

摘要

本综述聚焦于细胞外基质的主要成分——胶原蛋白是如何被分解代谢的。这一过程在正畸学的多个方面都很重要，因为基质在不断更新，其更新速率在胚胎发育、衰老、疾病以及诸如正畸牙齿移动等生理过程中有所不同。详细探讨每个过程并非本综述的目的。本文旨在清晰阐述基质金属蛋白酶（一类主要的蛋白酶），包括它们的分类、特性和功能。