Suppr超能文献

[厄瓜多尔患者中与抗疟疾治疗不依从相关的因素]

[The factors associated with noncompliance with antimalarial treatment in Ecuadorian patients].

作者信息

Yépez M C, Zambrano D, Carrasco F, Yépez R F

机构信息

Instituto Juan César García, Quito, Ecuador.

出版信息

Rev Cubana Med Trop. 2000 May-Aug;52(2):81-9.

Abstract

A total of 249 persons living in the northwest part of Ecuador with a clinical diagnosis of malaria confirmed by thick blood films were treated with chloroquine and primaquine according to the therapeutical system in force in the National Service for Eradication of Malaria. New clinical assessment and thick blood film were applied after 4 days in P. falciparum (n = 120) cases and after 8 days in P. vivax (n = 129) cases; patients were questioned about the compliance or non-compliance with the treatment, and the reasons for their acting in either way were studied. EPI-INFO 6.04 and SPSS PC 7.0 packages served to process the information: "kind adjustment test" (bondad de ajuste) abd factorial analysis of correspondences were used. The patient who daily took his/her pills for the number of days indicated, at the established intervals and at the right time was defined as a patient complying with the drug therapy. For every 3 patients complying with treatment, there were 2 who did not; non-compliance was not significantly related to age, sex, educational level, ethnic group, urban or rural setting or level of income, but learning about seriousness of the infection did help to compliance with the therapy. The reasons for non-compliance were mainly associated with drugs (side effects/reluctancy to take drugs), with the fact of forgetting to take them and of "getting cured quickly". The profile of the patient who did not comply with treatment corresponded to male, teenager, mixed race, poor and rural setting.

摘要

共有249名居住在厄瓜多尔西北部、经厚血膜确诊临床诊断为疟疾的患者,按照国家疟疾根除服务机构现行的治疗体系,接受了氯喹和伯氨喹治疗。恶性疟(n = 120)患者在4天后、间日疟(n = 129)患者在8天后进行了新的临床评估和厚血膜检查;询问患者对治疗的依从性或不依从性,并研究其这样做的原因。使用EPI-INFO 6.04和SPSS PC 7.0软件包处理信息:采用“拟合优度检验”(bondad de ajuste)和对应分析。每天按规定的天数、规定的间隔时间和正确的时间服药的患者被定义为依从药物治疗的患者。每3名依从治疗的患者中,就有2名不依从;不依从与年龄、性别、教育水平、种族、城乡环境或收入水平无显著关联,但了解感染的严重性确实有助于患者依从治疗。不依从的原因主要与药物(副作用/不愿服药)、忘记服药以及“很快治愈”的想法有关。不依从治疗的患者的特征为男性、青少年、混血儿、贫困且居住在农村地区。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验