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使用生物活性玻璃修复眶底骨折

Reconstruction of orbital floor fractures using bioactive glass.

作者信息

Kinnunen I, Aitasalo K, Pöllönen M, Varpula M

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Turku University Central Hospital, Finland.

出版信息

J Craniomaxillofac Surg. 2000 Aug;28(4):229-34. doi: 10.1054/jcms.2000.0140.

DOI:10.1054/jcms.2000.0140
PMID:11110155
Abstract

INTRODUCTION

The management of orbital floor fractures continues to be debated. Bioactive glasses and glass-ceramics are in the new group of materials developed for the repair of bone defects which are beyond any innate healing capacity due to their size.

OBJECTIVE

We compared the use of alloplastic implants (bioactive glass) with conventional autogenous grafts (cartilage--plus or minus Iyophilized dura) for the repair of orbital floor defects after trauma.

MATERIAL AND METHODS

Twenty-eight patients having orbital floor fractures with persistent diplopia, enophthalmos, and/or infraorbital nerve paraesthesia were operated on from 1991 to 1995 at Turku University Central Hospital. Reconstruction was either with bioactive glass (S93P4) or autogenous cartilage implants.

RESULTS

Postoperative tomograms in the 28 patients showed adequate maintenance of orbital and maxillary sinus volume without any evidence of resorption in either group. None of 14 patients in the study group had any evidence of dystopia or complications relating to implants follow-up. One had infraorbital nerve paraesthesia and another had entropion postoperatively. Among the 14 control subjects there were three cases of persistent diplopia, two of infraorbital nerve paraesthesia and one of enophthalmos.

CONCLUSION

Bioactive glass implants are well-tolerated and seem to be a promising repair material for orbital floor fractures. Their use leads to less morbidity as no donor site operation is needed. Also it provides favourable healing as it is bioactive, biocompatible and causes new bone formation.

摘要

引言

眶底骨折的治疗仍存在争议。生物活性玻璃和玻璃陶瓷属于为修复因尺寸过大而超出自身愈合能力的骨缺损所研发的新型材料。

目的

我们比较了异体植入物(生物活性玻璃)与传统自体移植物(软骨加或减冻干硬脑膜)在修复创伤后眶底缺损中的应用。

材料与方法

1991年至1995年期间,图尔库大学中心医院对28例患有眶底骨折且伴有持续性复视、眼球内陷和/或眶下神经感觉异常的患者进行了手术。采用生物活性玻璃(S93P4)或自体软骨植入物进行重建。

结果

28例患者术后的断层扫描显示眶部和上颌窦容积得到充分维持,两组均无吸收迹象。研究组的14例患者中,无一例出现植入物相关的错位或并发症迹象。1例患者术后出现眶下神经感觉异常,另1例出现睑内翻。在14例对照组患者中,有3例持续性复视、2例眶下神经感觉异常和1例眼球内陷。

结论

生物活性玻璃植入物耐受性良好,似乎是眶底骨折一种很有前景的修复材料。使用生物活性玻璃植入物无需进行供体部位手术,从而降低了发病率。此外,由于其具有生物活性、生物相容性并能促进新骨形成,因此愈合效果良好。

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