Brock L
Isr J Med Sci. 1975 Feb-Mar;11(2-3):122-9.
This paper is an analysis of the experiences of the author with patients under-going closed mitral valvotomy between 1948 and December 1963, and thus represents a follow-up of at least 10 years. Five hundred and seventy-one of 618 patients survived operation; the mortality rate of 7.6% is much higher than pertains at present. It includes the early pioneer days when many very ill patients were operated on. There were only five deaths in the most recent 400 consecutive cases. The mortality should be low today. A detailed follow-up shows that many patients are completely cured of their mitral stenosis: of 168 patients alive longer than 11 years, 41 survived for 11 to 15 years, 67 for 16 to 20 years and 60 for over 20 years. Restenosis was diagnosed in 128 patients (22.4%) and 93 of them had a second operation. When the valve is severely damaged, especially when it is regurgitant, the results are not as good and valve excision and replacement are often needed, but valvotomy for pure mitral stenosis can give excellent and lasting results.
本文分析了作者在1948年至1963年12月期间对接受闭式二尖瓣切开术患者的治疗经验,因此代表了至少10年的随访情况。618例患者中有571例术后存活;7.6%的死亡率远高于目前的水平。这其中包括早期的开拓阶段,当时许多病情严重的患者接受了手术。在最近连续的400例病例中仅有5例死亡。如今死亡率应该会很低。详细的随访显示,许多患者的二尖瓣狭窄已完全治愈:在存活超过11年的168例患者中,41例存活了11至15年,67例存活了16至20年,60例存活超过20年。128例患者(22.4%)被诊断为再狭窄,其中93例接受了二次手术。当瓣膜严重受损,尤其是出现反流时,治疗效果不佳,常需进行瓣膜切除和置换,但单纯二尖瓣狭窄的瓣膜切开术可取得优异且持久的效果。