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新型192铱高剂量率近距离放射治疗源的蒙特卡罗剂量测定法

Monte Carlo dosimetry of a new 192Ir high dose rate brachytherapy source.

作者信息

Angelopoulos A, Baras P, Sakelliou L, Karaiskos P, Sandilos P

机构信息

Physics Department, University of Athens, Panepistimioupolis, Ilisia, Greece.

出版信息

Med Phys. 2000 Nov;27(11):2521-7. doi: 10.1118/1.1315316.

Abstract

This work provides full dosimetric data for a new high-strength 192Ir source currently launched by Varian Oncology Systems for use in their high dose rate remote afterloading systems. The active core length of the new source is reduced to 5 mm compared to a value of 10 mm for the existing VariSource source design, with all other geometric source and encapsulation details being similar. Dose-rate constant, radial dose functions, geometry factors, and anisotropy functions, utilized in the AAPM Task Group 43 dose calculation formalism, were calculated using Monte Carlo simulation. Results are compared with corresponding data published for the existing VariSource and microSelectron high dose rate sources. The dose-rate constant for the new Varian source was found to be equal to 1.101 +/- 0.006cGyh(-1) U(-1), compared to values of 1.043 +/- 0.005 and 1.116 +/- 0.006 cGyh(-1) U(-1) calculated for the existing VariSource and microSelectron sources, respectively. The radial dose functions between the three sources are similar with the exception of their values at radial distances very close to the source (r approximately 2 mm) where differences of approximately 3% are observed. The new Varian source demonstrates a smaller anisotropy relative to the existing VariSource source design for polar angles close to the source longitudinal axis, due to its smaller active core length.

摘要

这项工作提供了瓦里安肿瘤系统公司目前推出的一种新型高强度192铱源的完整剂量学数据,该源用于其高剂量率远程后装系统。与现有的VariSource源设计的10毫米相比,新源的活性芯长度减少到了5毫米,其他所有源的几何形状和封装细节均相似。使用蒙特卡罗模拟计算了美国医学物理师协会任务组43剂量计算形式中使用的剂量率常数、径向剂量函数、几何因子和各向异性函数。将结果与已发表的现有VariSource和microSelectron高剂量率源的相应数据进行了比较。发现新瓦里安源的剂量率常数等于1.101±0.006cGyh(-1)U(-1),而现有VariSource源和microSelectron源计算得到的值分别为1.043±0.005和1.116±0.006cGyh(-1)U(-1)。除了在非常接近源的径向距离(r约为2毫米)处的值有所不同(观察到约3%的差异)外,这三种源之间的径向剂量函数相似。由于其活性芯长度较小,对于接近源纵轴的极角,新瓦里安源相对于现有的VariSource源设计表现出较小的各向异性。

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